HeterochromiaDifferently colored eyes; Eyes - different colors
Heterochromia is different colored eyes in the same person.
Heterochromia is uncommon in humans. However, it is quite common in dogs (such as Dalmatians and Australian sheep dogs), cats, and horses.
Most cases of heterochromia are hereditary, caused by a disease or syndrome, or due to an injury. Sometimes, one eye may change color following certain diseases or injuries.
Specific causes of eye color changes include:
- Bleeding (hemorrhage)
- Familial heterochromia
- Foreign object in the eye
- Glaucoma, or some medicines used to treat it
- Mild inflammation affecting only one eye
- Waardenburg syndrome
When to Contact a Medical Professional
Talk to your health care provider if you notice new changes in the color of one eye, or two differently colored eyes in your infant. A thorough eye exam is needed to rule out a medical problem.
Some conditions and syndromes associated with heterochromia, such as pigmentary glaucoma, can only be detected by a thorough eye exam.
What to Expect at Your Office Visit
Your provider may ask the following questions to help evaluate the cause:
- Did you notice the two different eye colors when the child was born, shortly after the birth, or recently?
- Are any other symptoms present?
An infant with heterochromia should be examined by both a pediatrician and an ophthalmologist for other possible problems.
A complete eye exam can rule out most causes of heterochromia. If there doesn't seem to be an underlying disorder, no further testing may be needed. If another disorder is suspected diagnostic tests, such as blood tests or chromosome studies, may be done to confirm the diagnosis.
Karyotyping is a test to examine chromosomes in a sample of cells. This test can help identify genetic problems as the cause of a disorder or diseas...Read Article Now Book Mark Article
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Olitsky SE, Hug D, Plummer LS, Stahl ED, Ariss MM, Lindquist TP. Abnormalities of pupil and iris. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics. 20th ed. Philadelphia, PA: Elsevier; 2016:chap 622.
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Heterochromia - illustration
Heterochromia is the presence of different colored eyes in the same person. Heterochromia in humans appears either as a hereditary trait unassociated with other disease, as a symptom of various syndromes or as the result of a trauma.
Review Date: 10/18/2017
Reviewed By: Neil K. Kaneshiro, MD, MHA, Clinical Professor of Pediatrics, University of Washington School of Medicine, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.