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Hydroxyzine overdose

Show Alternative Names
Vistaril overdose

Hydroxyzine is an antihistamine available only with a prescription. It is used to treat symptoms of allergies and motion sickness.

Hydroxyzine overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose.

This article is for information only. DO NOT use it to treat or manage an actual overdose. If you or someone you are with has an overdose, call your local emergency number (such as 911), or your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.

Poisonous Ingredient

Hydroxyzine can be harmful in large amounts.

Where Found

Hydroxyzine is found in medicines with these names:

  • Durrax
  • Rezine
  • Vistaril
  • Multipax

Other medicines may also contain hydroxyzine.

Symptoms

Dilated pupils are the classic symptom of a hydroxyzine overdose. Below are other symptoms of a hydroxyzine overdose in different parts of the body.

AIRWAYS AND LUNGS

BLADDER AND KIDNEYS

  • Difficulty urinating

EYES, EARS, NOSE, THROAT, AND MOUTH

HEART AND BLOOD

NERVOUS SYSTEM

  • Agitation
  • Coma (decreased level of consciousness and lack of responsiveness)
  • Seizures
  • Delirium
  • Depression
  • Disorientation
  • Dizziness
  • Drowsiness
  • Hallucinations (seeing or hearing things that aren't there)
  • Nervousness
  • Sleeping difficulties
  • Tremor
  • Uncoordinated movement
  • Unsteadiness

SKIN

STOMACH AND INTESTINES

  • Nausea
  • Vomiting

Before Calling Emergency

Have this information ready:

  • Person's age, weight, and condition
  • Name of the product (ingredients and strength, if known)
  • Time it was swallowed
  • Amount swallowed
  • If the medicine was prescribed for the person

Poison Control

Your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.

This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.

What to Expect at the Emergency Room

Take the container to the hospital with you, if possible.

The health care provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure.

Tests that may done include:

Treatment may include:
  • Fluids through a vein (by IV)
  • Medicines to treat symptoms
  • Activated charcoal
  • Laxative
  • Breathing support, including a tube through the mouth into the lungs and connected to a breathing machine (ventilator)

Outlook (Prognosis)

Recovery is likely if the person survives the first 24 hours. Complications such as pneumonia, muscle damage from lying on a hard surface for a prolonged period of time, or brain damage from lack of oxygen may cause permanent disability. Few people actually die from an antihistamine overdose, unless they have serious heart rhythm disturbances or breathing problems.

Keep all medicines in child-proof bottles and out of reach of children.

Review Date: 11/2/2023

Reviewed By

Jesse Borke, MD, CPE, FAAEM, FACEP, Attending Physician at Kaiser Permanente, Orange County, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

References

Aronson JK. Anticholinergic drugs. In: Aronson JK, ed. Meyler's Side Effects of Drugs. 16th ed. Waltham, MA: Elsevier; 2016:534-539.

Hoppe JA, Monte AA. Anticholinergics. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 140.

Disclaimer

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. No warranty of any kind, either expressed or implied, is made as to the accuracy, reliability, timeliness, or correctness of any translations made by a third-party service of the information provided herein into any other language. © 1997- A.D.A.M., a business unit of Ebix, Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

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Allergies - Animation

Blooming flowers and blossoming trees are signs that spring has arrived. But for some people, those blossoms and blooms are also signs that allergy season is under way. And that means months of sniffling, sneezing, and runny eyes ahead.

You may know that you have allergies as soon as you step outside on a spring day, eat peanuts, or pet your dog. Signs of an allergy may include trouble breathing, teary eyes, hives, itching, or vomiting after you come in contact with your allergy trigger.

Your doctor can also do allergy tests to find out whether you're allergic, and what triggers your allergies. The most common type of allergy test is a skin test. The doctor puts a small amount of different allergy-causing substances under your skin. Then you wait for signs of a reaction, like swelling or redness. You might also have blood tests to check for chemicals that are related to allergies.

So, how are allergies treated?

There are a few medicines you can buy at your local drugstore or your doctor can prescribe to treat your allergies. Antihistamines prevent histamine chemicals from triggering allergy symptoms. Decongestants shrink swollen blood vessels throughout your body, including inside your nose, perhaps helping you breathe easier. Steroid drugs reduce swelling and inflammation. And Leukotriene inhibitors block the substances that trigger allergies. If your allergy is really bugging you, your doctor may give you allergy shots. When you take allergy shots over time, eventually they can help your body get used to the substance so you don't over-react to it in the future.

Usually you can relieve allergies by taking medicine and avoiding whatever it is that triggers them. But in some people, allergies to insect stings or certain foods, like peanuts, cause a life-threatening reaction. This is called anaphylaxis. And if you have a life-threatening allergic reaction, call immediately for emergency medical help.

 

Allergies - Animation

Blooming flowers and blossoming trees are signs that spring has arrived. But for some people, those blossoms and blooms are also signs that allergy season is under way. And that means months of sniffling, sneezing, and runny eyes ahead.

You may know that you have allergies as soon as you step outside on a spring day, eat peanuts, or pet your dog. Signs of an allergy may include trouble breathing, teary eyes, hives, itching, or vomiting after you come in contact with your allergy trigger.

Your doctor can also do allergy tests to find out whether you're allergic, and what triggers your allergies. The most common type of allergy test is a skin test. The doctor puts a small amount of different allergy-causing substances under your skin. Then you wait for signs of a reaction, like swelling or redness. You might also have blood tests to check for chemicals that are related to allergies.

So, how are allergies treated?

There are a few medicines you can buy at your local drugstore or your doctor can prescribe to treat your allergies. Antihistamines prevent histamine chemicals from triggering allergy symptoms. Decongestants shrink swollen blood vessels throughout your body, including inside your nose, perhaps helping you breathe easier. Steroid drugs reduce swelling and inflammation. And Leukotriene inhibitors block the substances that trigger allergies. If your allergy is really bugging you, your doctor may give you allergy shots. When you take allergy shots over time, eventually they can help your body get used to the substance so you don't over-react to it in the future.

Usually you can relieve allergies by taking medicine and avoiding whatever it is that triggers them. But in some people, allergies to insect stings or certain foods, like peanuts, cause a life-threatening reaction. This is called anaphylaxis. And if you have a life-threatening allergic reaction, call immediately for emergency medical help.

 
 
 
 

 

 
 
 
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