Sulindac overdose
Clinoril overdoseSulindac is a nonsteroidal anti-inflammatory drug (NSAID). It is used to relieve pain and swelling associated with certain types of arthritis. Sulindac overdose occurs when someone takes more than the recommended amount of this medicine. People with kidney or liver disease are more likely to develop serious side effects or worsening of their disease from NSAIDs.
As a group, and because of their common use, NSAIDs are responsible for more serious drug-related side effects than any other class of pain-relieving drugs.
This article is for information only. DO NOT use it to treat or manage an actual overdose. If you or someone you are with overdoses, call the local emergency number (such as 911), or the local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.
Overdose
An overdose is when you take more than the recommended amount of something, often a medicine or drug. An overdose may result in serious, harmful sym...
Read Article Now Book Mark ArticlePoisonous Ingredient
Sulindac
Symptoms
Symptoms of a sulindac overdose may include:
Airways and lungs:
- Rapid breathing (hyperventilation)
Rapid breathing
Hyperventilation is rapid and deep breathing. It is also called overbreathing, and it may leave you feeling breathless.
Read Article Now Book Mark Article - Slow, labored breathing
Labored breathing
Most people take breathing for granted. People with certain illnesses may have breathing problems that they deal with on a regular basis. This arti...
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Eyes, ears, nose, and throat:
- Ringing in the ears
Ringing in the ears
Tinnitus is the medical term for "hearing" noises in your ears. It occurs when there is no outside source of the sounds. Tinnitus is often called "r...
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Blurred vision
There are many types of eye problems and vision disturbances, such as: Halos Blurred vision (the loss of sharpness of vision and the inability to see...
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Nervous system:
- Agitation, confusion, incoherence (not understandable)
Agitation
Agitation is an unpleasant state of extreme arousal. An agitated person may feel stirred up, excited, tense, confused, or irritable.
Read Article Now Book Mark Article - Drowsiness or even coma (unresponsiveness)
Drowsiness
Drowsiness refers to feeling more sleepy than normal during the day. People who are drowsy may fall asleep when they do not want to or at times whic...
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Decreased alertness is a state of reduced awareness and is often a serious condition. A coma is the most severe state of decreased alertness from whi...
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Convulsions
A seizure is the physical changes in behavior that occurs during an episode of specific types of abnormal electrical activity in the brain. The term ...
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- Unsteadiness, movement problems
Unsteadiness
Walking abnormalities can be caused by many different types of problems. Problems with the joints, (such as arthritis), bones (such as deformities),...
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Skin:
- Rash
Stomach and intestines:
- Diarrhea
- Heartburn
- Nausea, vomiting (sometimes bloody)
- Stomach or abdominal pain
Before Calling Emergency
The following information is helpful for emergency assistance:
- The person's age, weight, and condition
- The name of product (as well as the ingredients and strength if known)
- The time it was swallowed
- The amount swallowed
- If the medicine was prescribed for the person
However, DO NOT delay calling for help if this information is not immediately available.
Poison Control
Your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.
Poison control center
For a POISON EMERGENCY call:1-800-222-1222ANYWHERE IN THE UNITED STATESThis national hotline number will let you talk to experts in poisoning. This ...
Read Article Now Book Mark ArticleThis is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week.
What to Expect at the Emergency Room
The health care provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms will be treated as appropriate. The person may receive:
- Activated charcoal
- Airway support, including oxygen, breathing tube through the mouth (intubation),and ventilator (breathing machine)
- Blood and urine tests
- Chest x-ray
- ECG (electrocardiogram, or heart tracing)
- Fluids through the vein (intravenous or IV)
- Laxative
- Medicines to treat symptoms
In the rare, more serious case, additional treatment may be needed. Most people will be discharged from the emergency department after a period of observation.
Outlook (Prognosis)
Recovery is likely. In rare cases, kidney damage may be permanent and require long-term dialysis.
References
Aronson JK. Sulindac. In: Aronson JK, ed. Meyler's Side Effects of Drugs. 16th ed. Waltham, MA: Elsevier; 2016:591-594.
Hatten BW. Aspirin and nonsteroidal agents. In: Walls RM, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 139.
Review Date: 1/2/2023
Reviewed By: Jesse Borke, MD, CPE, FAAEM, FACEP, Attending Physician at Kaiser Permanente, Orange County, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.