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Cytochrome b5 reductase

Cytochrome b5 reductase is an enzyme in the blood. It controls the amount of iron in your red blood cells, and helps the cells carry the normal amount of oxygen.

Enzyme

Enzymes are complex proteins that cause a specific chemical change. For example, they can help break down the foods we eat so the body can use them....

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People who do not have enough of this enzyme may develop a condition called methemoglobinemia.

Methemoglobinemia

Methemoglobinemia (MetHb) is a blood disorder in which an abnormal amount of methemoglobin is produced. Hemoglobin is the protein in red blood cells...

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Review Date: 1/25/2022

Reviewed By

Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

References

Means RT. Approach to the anemias. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 149.

Smith-Whitley K, Kwiatkowski JL. Hemoglobinopathies. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 489.

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Cytochrome b5 reductase

Enzyme

Methemoglobinemia

Reviewed By

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