BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuNecrosisNecrosis is the death of body tissue. It occurs when too little blood flows to the tissue. This can be from injury, radiation, or chemicals. Necrosis cannot be reversed.When large areas of tissue die due to a lack of blood supply, the condition is called gangrene.GangreneGangrene is the death of tissue in part of the body.ImageRead Article Now Book Mark Article Open ReferencesReferencesOakes SA. Cell injury, cell death, and adaptations. In: Kumar V, Abbas AK, Aster JC, eds. Robbins & Cotran Pathologic Basis of Disease. 10th ed. Philadelphia, PA: Elsevier;2021:chap 2.AllVideoImagesTogMeningococcemia on the calves - illustration Meningococcemia is a life-threatening infection that occurs when the meningococcus, Neisseria meningitidis, invades the blood stream. Bleeding into the skin (petechiae and purpura) may occur. The tissue in areas may die (become necrotic or gangrenous). If the person survives, the areas heal with scarring.Meningococcemia on the calvesillustrationMeningococcemia on the leg - illustration Meningococcemia is a life-threatening infection that occurs when the meningococcus, Neisseria meningitidis, invades the blood stream. There is usually bleeding into the skin (petechiae and purpura), and the tissue in these areas may die (become necrotic or gangrenous). If the patient survives, the areas heal with scarring. This picture demonstrates more hemorrhage and little tissue death.Meningococcemia on the legillustrationMeningococcemia associated purpura - illustration Meningococcemia is a life-threatening infection that occurs when the bacteria, Neisseria meningitidis, invades the blood stream. Bleeding into the skin (petechiae and purpura) typically occurs and the tissue may die (become necrotic or gangrenous). If the patient survives, the areas heal with scarring.Meningococcemia associated purpuraillustrationNecrosis of the toes - illustration Necrosis is death of a portion of tissue or an organ in the body. Tissue death occurs when there is not enough blood supplied to the area, whether from trauma, radiation, or chemicals. Once necrosis is confirmed, it is not reversible.Necrosis of the toesillustrationMeningococcemia on the calves - illustration Meningococcemia is a life-threatening infection that occurs when the meningococcus, Neisseria meningitidis, invades the blood stream. Bleeding into the skin (petechiae and purpura) may occur. The tissue in areas may die (become necrotic or gangrenous). If the person survives, the areas heal with scarring.Meningococcemia on the calvesillustrationMeningococcemia on the leg - illustration Meningococcemia is a life-threatening infection that occurs when the meningococcus, Neisseria meningitidis, invades the blood stream. There is usually bleeding into the skin (petechiae and purpura), and the tissue in these areas may die (become necrotic or gangrenous). If the patient survives, the areas heal with scarring. This picture demonstrates more hemorrhage and little tissue death.Meningococcemia on the legillustrationMeningococcemia associated purpura - illustration Meningococcemia is a life-threatening infection that occurs when the bacteria, Neisseria meningitidis, invades the blood stream. Bleeding into the skin (petechiae and purpura) typically occurs and the tissue may die (become necrotic or gangrenous). If the patient survives, the areas heal with scarring.Meningococcemia associated purpuraillustrationNecrosis of the toes - illustration Necrosis is death of a portion of tissue or an organ in the body. Tissue death occurs when there is not enough blood supplied to the area, whether from trauma, radiation, or chemicals. Once necrosis is confirmed, it is not reversible.Necrosis of the toesillustrationRelated Information Review Date: 9/18/2023 Reviewed By: Anna C. Edens Hurst, MD, MS, Associate Professor in Medical Genetics, The University of Alabama at Birmingham, Birmingham, AL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. 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NecrosisNecrosis is the death of body tissue. It occurs when too little blood flows to the tissue. This can be from injury, radiation, or chemicals. Necrosis cannot be reversed.When large areas of tissue die due to a lack of blood supply, the condition is called gangrene.GangreneGangrene is the death of tissue in part of the body.ImageRead Article Now Book Mark Article Open ReferencesReferencesOakes SA. Cell injury, cell death, and adaptations. In: Kumar V, Abbas AK, Aster JC, eds. Robbins & Cotran Pathologic Basis of Disease. 10th ed. Philadelphia, PA: Elsevier;2021:chap 2.