Sporotrichosis
Sporotrichosis is a long-term (chronic) skin infection that is caused by a fungus called Sporothrix schenckii.
Chronic
Chronic refers to something that continues over an extended period of time. A chronic condition is usually long-lasting and does not easily or quick...
Causes
Sporothrix schenckii is found in plants. Infection commonly occurs when the skin is broken while handling plant material such as rosebushes, briars, or dirt that contains a lot of mulch.
Sporotrichosis can be a job-related disease for people who work with plants, such as farmers, horticulturists, rose gardeners, and plant nursery workers. Widespread (disseminated) sporotrichosis can develop in people with a weakened immune system when they inhale dust filled with spores of the fungus.
Symptoms
Symptoms include a small, painless, red lump that develops at the site of infection. As time passes, this lump will turn into an ulcer (sore). The lump may develop up to 3 months after an injury.
Ulcer
Erosion is a breakdown of the outer layers of the skin, usually because of a: CutScrapeInflammation
Most sores are on the hands and forearms because these areas are commonly injured when handling plants.
The fungus follows the channels in your body's lymph system. Small ulcers appear as lines on the skin as the infection moves up an arm or leg. These sores do not heal unless they are treated, and they may last for years. The sores may sometimes drain small amounts of pus.
Body-wide (systemic) sporotrichosis can cause lung and breathing problems, bone infection, arthritis, and infection of the nervous system.
Systemic
Systemic means affecting the entire body, rather than a single organ or body part. For example, systemic disorders, such as high blood pressure, or s...
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Your health care provider will examine you and ask about your symptoms. The examination will show the typical sores caused by the fungus. Sometimes, a small sample of affected tissue is removed, examined under a microscope, and tested in a lab to identify the fungus.
Treatment
The skin infection is often treated with an antifungal medicine called itraconazole. It is taken by mouth and continued for 2 to 4 weeks after the skin sores have cleared. You may have to take the medicine for 3 to 6 months. A medicine called terbinafine may be used instead of itraconazole.
Infections that have spread or affect the entire body are often treated with amphotericin B, or sometimes itraconazole. Therapy for systemic disease can last up to 12 months.
Outlook (Prognosis)
With treatment, full recovery is likely. Disseminated sporotrichosis is more difficult to treat and requires several months of therapy. Disseminated sporotrichosis can be life threatening for people with a weakened immune system.
Possible Complications
People with a healthy immune system may have:
- Discomfort
- Secondary skin infections (such as staph or strep)
People with a weakened immune system may develop:
Weakened immune system
Immunodeficiency disorders occur when the body's immune response is reduced or absent.
- Arthritis
Arthritis
Arthritis is inflammation or degeneration of one or more joints. A joint is the area where 2 bones meet. There are more than 100 different types of...
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- Complications from medicines -- amphotericin B can have serious side effects, including kidney damage and changes in blood chemistries
- Lung and breathing problems (such as pneumonia)
Pneumonia
Pneumonia is a breathing (respiratory) condition in which there is an infection of the lung. This article covers community-acquired pneumonia (CAP). ...
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Brain infection (meningitis)
Meningitis
Meningitis is an infection of the membranes covering the brain and spinal cord. This covering is called the meninges.
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When to Contact a Medical Professional
Contact your provider if you develop persistent skin lumps or skin ulcers that do not go away. Tell your provider if you know that you were exposed to plants from gardening.
Skin lumps
Skin lumps are any abnormal bumps or swellings on or under the skin.
Prevention
People with a weakened immune system should try to reduce risk for skin injury. Wearing thick gloves while gardening can help.
References
Rex JH, Okhuysen PC. Sporothrix schenckii. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 259.
Thompson GR, Miceli MH. Endemic mycoses. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 308.
Sporotrichosis on the hand and arm - illustration
Sporotrichosis is a fungal infection that frequently occurs following a minor injury while gardening or farming. Spores, which live in vegetation, enter the skin and begin to grow. The fungus follows the lymph channels up the extremity. Granulomatous lesions develop along the lymph channel, ulcerate, and drain. If left untreated, this condition can persist for years.
Sporotrichosis on the hand and arm
illustration
Sporotrichosis on the arm - illustration
Sporotrichosis is a fungal infection that frequently occurs following a minor injury while gardening or farming. Spores, which live in vegetation, enter the skin and begin to grow. The fungus follows the lymph channels up the extremity. Granulomatous lesions develop along the lymph channel, ulcerate, and drain. If left untreated, this condition can persist for years.
Sporotrichosis on the arm
illustration
Sporotrichosis on the forearm - illustration
Sporotrichosis is a fungal infection that frequently occurs following a minor injury while gardening or farming. Spores, which live in vegetation, enter the skin and begin to grow. The fungus follows the lymph channels up the extremity. Granulomatous lesions develop along the lymph channel, ulcerate, and drain. If left untreated, this condition can persist for years.
Sporotrichosis on the forearm
illustration
Fungus - illustration
Fungal infections are caused by microscopic organisms (fungi) that can live on the skin. They can live on the dead tissues of the hair, nails, and outer skin layers.
Fungus
illustration
Sporotrichosis on the hand and arm - illustration
Sporotrichosis is a fungal infection that frequently occurs following a minor injury while gardening or farming. Spores, which live in vegetation, enter the skin and begin to grow. The fungus follows the lymph channels up the extremity. Granulomatous lesions develop along the lymph channel, ulcerate, and drain. If left untreated, this condition can persist for years.
Sporotrichosis on the hand and arm
illustration
Sporotrichosis on the arm - illustration
Sporotrichosis is a fungal infection that frequently occurs following a minor injury while gardening or farming. Spores, which live in vegetation, enter the skin and begin to grow. The fungus follows the lymph channels up the extremity. Granulomatous lesions develop along the lymph channel, ulcerate, and drain. If left untreated, this condition can persist for years.
Sporotrichosis on the arm
illustration
Sporotrichosis on the forearm - illustration
Sporotrichosis is a fungal infection that frequently occurs following a minor injury while gardening or farming. Spores, which live in vegetation, enter the skin and begin to grow. The fungus follows the lymph channels up the extremity. Granulomatous lesions develop along the lymph channel, ulcerate, and drain. If left untreated, this condition can persist for years.
Sporotrichosis on the forearm
illustration
Fungus - illustration
Fungal infections are caused by microscopic organisms (fungi) that can live on the skin. They can live on the dead tissues of the hair, nails, and outer skin layers.
Fungus
illustration
Review Date: 3/16/2024
Reviewed By: Jatin M. Vyas, MD, PhD, Associate Professor in Medicine, Harvard Medical School; Associate in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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