Schistosomiasis
Bilharzia; Katayama fever; Swimmer's itch; Blood fluke; Snail feverSchistosomiasis is an infection with a type of blood fluke parasite called schistosomes.
Causes
You can get a schistosoma infection through contact with contaminated water. This parasite swims freely in open bodies of fresh water.
When the parasite comes into contact with humans, it burrows into the skin and matures into another stage. Then, it travels to the lungs and liver, where it grows into the adult form of the worm.
The adult worm then travels to its preferred body part, depending on its species. These areas include the:
- Bladder
- Rectum
- Intestines
- Liver
- Veins that carry blood from the intestines to the liver
- Spleen
- Lungs
Schistosomiasis is not usually seen in the United States except for returning travelers or people from other countries who have the infection and are now living in the United States. It is common in many tropical and subtropical areas worldwide.
Symptoms
Symptoms vary with the species of worm and the phase of infection.
- Many parasites may cause fever, chills, swollen lymph nodes, and swollen liver and spleen.
- When the worm first gets into the skin, it may cause itching and a rash (swimmer's itch). In this condition, the schistosome is destroyed within the skin.
- Intestinal symptoms include abdominal pain and diarrhea (which may be bloody).
- Urinary symptoms may include frequent urination, painful urination, and blood in the urine.
Exams and Tests
Your health care provider will examine you. Tests that may be done include:
- Antibody test to check for signs of infection
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Biopsy of tissue
Biopsy
A biopsy is the removal of a small piece of tissue for laboratory examination.
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Complete blood count (CBC) to check for signs of anemia
Complete blood count (CBC)
A complete blood count (CBC) test measures the following:The number of white blood cells (WBC count)The number of red blood cells (RBC count)The numb...
Read Article Now Book Mark Article - Eosinophil count to measure the number of eosinophils, a type of white blood cell
- Kidney function tests
- Liver function tests
- Stool examination to look for parasite eggs
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Urinalysis to look for parasite eggs
Urinalysis
Urinalysis is the physical, chemical, and microscopic examination of urine. It involves a number of tests to detect and measure various compounds th...
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Treatment
This infection is usually treated with the drug praziquantel or oxamniquine. This is usually given along with corticosteroids. If the infection is severe or involves the brain, corticosteroids may be given first.
Outlook (Prognosis)
Treatment before significant damage or severe complications occur usually produces good results.
Possible Complications
These complications may occur:
- Bladder cancer
-
Chronic kidney failure
Chronic kidney failure
Chronic kidney disease is the slow loss of kidney function over time. The main job of the kidneys is to remove wastes and excess water from the body...
Read Article Now Book Mark Article - Chronic liver damage and an enlarged spleen
- Colon (large intestine) inflammation
- Kidney and bladder blockage
-
High blood pressure in the arteries of the lungs (pulmonary hypertension)
Pulmonary hypertension
Pulmonary hypertension is high blood pressure in the pulmonary arteries of the lungs. It makes the right side of the heart work harder than normal....
Read Article Now Book Mark Article - Repeated blood infections, if bacteria enter the bloodstream through an irritated colon
- Right-sided heart failure
-
Seizures
Seizures
A seizure is the physical changes in behavior that occurs during an episode of specific types of abnormal electrical activity in the brain. The term ...
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When to Contact a Medical Professional
Contact your provider if you develop symptoms of schistosomiasis, especially if you have:
- Traveled to a tropical or subtropical area where the disease is known to exist
- Been exposed to contaminated or possibly contaminated bodies of water
Prevention
Follow these steps to avoid getting this infection:
- Avoid swimming or bathing in contaminated or potentially contaminated water.
- Avoid bodies of water if you do not know whether they are safe.
Snails can host this parasite and are part of its normal life cycle. Getting rid of snails in bodies of water used by humans may help prevent infection.
References
Carvalho EM, Lima AAM, Marcos LA, Gotuzzo E. Trematode infections. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 334.
Maguire JH. Trematodes (schistosomes and liver, intestinal, and lung flukes). In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 288.
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Swimmer's itch - illustration
Swimmer's itch is caused by parasites found in contaminated water. The parasite enters through the skin and a rash appears at the site of entry. In some tropical countries, the parasite found in the contaminated water is capable of producing a severe disease.
Swimmer's itch
illustration
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Antibodies - illustration
Antigens are large molecules (usually proteins) on the surface of cells, viruses, fungi, bacteria, and some non-living substances such as toxins, chemicals, drugs, and foreign particles. The immune system recognizes antigens and produces antibodies that destroy substances containing antigens.
Antibodies
illustration
-
Swimmer's itch - illustration
Swimmer's itch is caused by parasites found in contaminated water. The parasite enters through the skin and a rash appears at the site of entry. In some tropical countries, the parasite found in the contaminated water is capable of producing a severe disease.
Swimmer's itch
illustration
-
Antibodies - illustration
Antigens are large molecules (usually proteins) on the surface of cells, viruses, fungi, bacteria, and some non-living substances such as toxins, chemicals, drugs, and foreign particles. The immune system recognizes antigens and produces antibodies that destroy substances containing antigens.
Antibodies
illustration
Review Date: 12/4/2022
Reviewed By: Jatin M. Vyas, MD, PhD, Associate Professor in Medicine, Harvard Medical School; Associate in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.