Byssinosis
Cotton worker's lung; Cotton bract disease; Mill fever; Brown lung disease; Monday feverByssinosis is a disease of the lungs. It is caused by breathing in (inhaling) cotton dust or dusts from other vegetable fibers such as flax, hemp, or sisal while at work.
Causes
Inhaling the dust produced by raw cotton can cause byssinosis. It is most common in people who work in the textile industry.
Those who are sensitive to the dust can have an asthma-like condition after being exposed.
Asthma-like condition
Occupational asthma is a lung disorder in which substances found in the workplace cause the airways of the lungs to swell and narrow. This leads to ...

Methods of prevention in the United States have reduced the number of cases. Byssinosis is still common in developing countries. Smoking increases risk of developing this disease. Being exposed to the dust many times can lead to long-term (chronic) lung disease.
Symptoms
Symptoms may include any of the following:
- Chest tightness
-
Cough
Cough
Coughing is an important way to keep your throat and airways clear. But too much coughing may mean you have a disease or disorder. Some coughs are d...
ImageRead Article Now Book Mark Article -
Wheezing
Wheezing
Wheezing is a high-pitched whistling sound during breathing. It occurs when air moves through narrowed breathing tubes in the lungs.
ImageRead Article Now Book Mark Article - Shortness of breath
Symptoms are worse at the beginning of the work week and improve later in the week. Symptoms are also less severe when the person is away from the workplace.
Exams and Tests
Your health care provider will take your medical history. You'll be asked if your symptoms relate to certain exposures or times of exposure. Your provider will also do a physical exam, paying special attention to the lungs.
Tests that may be ordered include:
-
Chest x-ray
Chest x-ray
A chest x-ray is an x-ray of the chest, lungs, heart, large arteries, ribs, and diaphragm.
ImageRead Article Now Book Mark Article -
Chest CT scan
Chest CT scan
A chest CT (computed tomography) scan is an imaging method that uses x-rays to create cross-sectional pictures of the chest and upper abdomen....
ImageRead Article Now Book Mark Article -
Lung function tests
Lung function tests
Pulmonary function tests are a group of tests that measure breathing and how well the lungs are functioning.
ImageRead Article Now Book Mark Article
Treatment
The most important treatment is to stop being exposed to the dust. Reducing dust levels in the factory (by improving machinery or ventilation) will help prevent byssinosis. Some people may have to change jobs to avoid further exposure.
Medicines used for asthma, such as bronchodilators, usually improve symptoms. Corticosteroid medicines may be prescribed in more severe cases.
Stopping smoking is very important for people with this condition. Breathing treatments, including nebulizers, may be prescribed if the condition becomes long-term. Home oxygen therapy may be needed if blood oxygen level is low.
Nebulizers
A nebulizer is a small machine that turns liquid medicine into a mist that can be easily inhaled. You sit with the machine and breathe in the medici...

People with a long-term (chronic) lung disease can be helped with:
- Physical exercise programs
- Breathing exercises
- Patient education programs
Outlook (Prognosis)
Stopping exposure to the dust often improves symptoms. Continued exposure can lead to reduced lung function. In the United States, worker's compensation may be available to people with byssinosis.
Possible Complications
Chronic bronchitis may develop. This is swelling (inflammation) of the large airways of the lungs with a large amount of phlegm production. Continued exposure can lead to end-stage lung disease.
Chronic bronchitis
Industrial bronchitis is swelling (inflammation) of the large airways of the lungs that occurs in some people who work around certain dusts, fumes, s...

When to Contact a Medical Professional
Contact your provider if you:
- Have symptoms of byssinosis and know you have been exposed to cotton or other fibers
- Think you have been exposed to cotton or other fiber dust at work and you have breathing problems
Having byssinosis makes it easier for you to develop lung infections. So if you've been diagnosed with byssinosis, contact your provider right away if you develop:
- A cough
- Shortness of breath
- Fever
- Other signs of a lung infection
- Symptoms of the flu or COVID-19
Since your lungs are already damaged, it's important to have the infection treated right away. This will prevent breathing problems from becoming severe. It will also prevent further damage to your lungs.
Talk to your provider about getting the flu, pneumonia, and other recommended vaccines.
Prevention
Controlling dust, using face masks, and other measures can reduce the risk. Stop smoking, especially if you work in textile manufacturing.
References
Go LHT, Cohen RA. Pneumoconioses. In: Broaddus VC, Ernst JD, King TE, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 7th ed. Philadelphia, PA: Elsevier; 2022:chap 101.
Tarlo SM. Occupational lung disease. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 87.
-
Lungs - illustration
The major features of the lungs include the bronchi, the bronchioles and the alveoli. The alveoli are the microscopic blood vessel-lined sacks in which oxygen and carbon dioxide gas are exchanged.
Lungs
illustration
Review Date: 5/3/2023
Reviewed By: Denis Hadjiliadis, MD, MHS, Paul F. Harron, Jr. Professor of Medicine, Pulmonary, Allergy, and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.