BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuHereditary ovalocytosisOvalocytosis - hereditaryHereditary ovalocytosis is a rare condition passed down through families (inherited). The blood cells are oval-shaped instead of round. It is a form of hereditary elliptocytosis.Hereditary elliptocytosisHereditary elliptocytosis is a disorder passed down through families in which the red blood cells are abnormally shaped. It is similar to other bloo...ImageRead Article Now Book Mark Article Causes Ovalocytosis is mainly found in Southeast Asian populations. Symptoms Newborn infants with ovalocytosis may have anemia and jaundice. Adults most often do not show symptoms.AnemiaAnemia is a condition in which the body does not have enough healthy red blood cells. Red blood cells provide oxygen to body tissues. Different type...ImageRead Article Now Book Mark Article JaundiceJaundice is a yellow color of the skin, mucus membranes, or eyes. The yellow coloring comes from bilirubin, a byproduct of old red blood cells. Jau...ImageRead Article Now Book Mark Article Exams and Tests An exam by your health care provider may show an enlarged spleen.This condition is diagnosed by looking at the shape of blood cells under a microscope. The following tests may also be done:Complete blood count (CBC) to check for anemia or red blood cell destruction Complete blood countA complete blood count (CBC) test measures the following:The number of white blood cells (WBC count)The number of red blood cells (RBC count)The numb...ImageRead Article Now Book Mark Article Blood smear to determine cell shape Bilirubin level (may be high) Bilirubin levelThe bilirubin blood test measures the level of bilirubin in the blood. Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. Bi...ImageRead Article Now Book Mark Article Lactate dehydrogenase level (may be high) Ultrasound of the abdomen (may show gallstones) Treatment In severe cases, the disease may be treated by removal of the spleen (splenectomy).SplenectomySpleen removal is surgery to remove a diseased or damaged spleen. This surgery is called splenectomy. The spleen is in the upper part of the belly, ...ImageRead Article Now Book Mark Article Possible Complications The condition may be associated with gallstones or kidney problems.GallstonesGallstones are hard deposits that form inside the gallbladder. These may be as small as a grain of sand or as large as a golf ball.ImageRead Article Now Book Mark Article Open ReferencesReferencesGallagher PG. Hemolytic anemias: red blood cell membrane and metabolic defects. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 152.Gallagher PG. Red blood cell membrane disorders. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 7th ed. Philadelphia, PA: Elsevier; 2018:chap 45.Merguerian MD, Gallagher PG. Hereditary elliptocytosis, hereditary pyropoikilocytosis, and related disorders. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 486.AllVideoImagesTogOvalocytosis - illustration OvalocytosisillustrationBlood cells - illustration Blood is comprised of red blood cells, platelets, and various white blood cells.Blood cellsillustrationOvalocytosis - illustration OvalocytosisillustrationBlood cells - illustration Blood is comprised of red blood cells, platelets, and various white blood cells.Blood cellsillustrationRelated Information Hereditary elliptocytosis(Condition)Hemolytic anemia(Condition)Spleen removal(Surgery) Review Date: 1/25/2022 Reviewed By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. 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Hereditary ovalocytosisOvalocytosis - hereditaryHereditary ovalocytosis is a rare condition passed down through families (inherited). The blood cells are oval-shaped instead of round. It is a form of hereditary elliptocytosis.Hereditary elliptocytosisHereditary elliptocytosis is a disorder passed down through families in which the red blood cells are abnormally shaped. It is similar to other bloo...ImageRead Article Now Book Mark Article Causes Ovalocytosis is mainly found in Southeast Asian populations. Symptoms Newborn infants with ovalocytosis may have anemia and jaundice. Adults most often do not show symptoms.AnemiaAnemia is a condition in which the body does not have enough healthy red blood cells. Red blood cells provide oxygen to body tissues. Different type...ImageRead Article Now Book Mark Article JaundiceJaundice is a yellow color of the skin, mucus membranes, or eyes. The yellow coloring comes from bilirubin, a byproduct of old red blood cells. Jau...ImageRead Article Now Book Mark Article Exams and Tests An exam by your health care provider may show an enlarged spleen.This condition is diagnosed by looking at the shape of blood cells under a microscope. The following tests may also be done:Complete blood count (CBC) to check for anemia or red blood cell destruction Complete blood countA complete blood count (CBC) test measures the following:The number of white blood cells (WBC count)The number of red blood cells (RBC count)The numb...ImageRead Article Now Book Mark Article Blood smear to determine cell shape Bilirubin level (may be high) Bilirubin levelThe bilirubin blood test measures the level of bilirubin in the blood. Bilirubin is a yellowish pigment found in bile, a fluid made by the liver. Bi...ImageRead Article Now Book Mark Article Lactate dehydrogenase level (may be high) Ultrasound of the abdomen (may show gallstones) Treatment In severe cases, the disease may be treated by removal of the spleen (splenectomy).SplenectomySpleen removal is surgery to remove a diseased or damaged spleen. This surgery is called splenectomy. The spleen is in the upper part of the belly, ...ImageRead Article Now Book Mark Article Possible Complications The condition may be associated with gallstones or kidney problems.GallstonesGallstones are hard deposits that form inside the gallbladder. These may be as small as a grain of sand or as large as a golf ball.ImageRead Article Now Book Mark Article Open ReferencesReferencesGallagher PG. Hemolytic anemias: red blood cell membrane and metabolic defects. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 152.Gallagher PG. Red blood cell membrane disorders. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 7th ed. Philadelphia, PA: Elsevier; 2018:chap 45.Merguerian MD, Gallagher PG. Hereditary elliptocytosis, hereditary pyropoikilocytosis, and related disorders. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 486.