Hepatic ischemiaIschemic hepatitis; Shock liver
Hepatic ischemia is a condition in which the liver does not get enough blood or oxygen. This causes injury to liver cells.
Low blood pressure from any condition can lead to hepatic ischemia. Such conditions may include:
Low blood pressure
Low blood pressure occurs when blood pressure is much lower than normal. This means the heart, brain, and other parts of the body do not get enough ...Read Article Now Book Mark Article
Other causes may include:
- Blood clots in the main artery to the liver (hepatic artery) after a liver transplant
- Swelling of blood vessels leading to reduced blood flow (vasculitis)
- Heat stroke
The person may have altered mental status due to reduced blood flow to the brain. Other symptoms may include:
- Loss of appetite
- Feeling of general discomfort
Damage to the liver cells most often does not cause symptoms until it affects liver function.
Blood clots in the liver's main artery may cause abdominal pain.
Exams and Tests
The following tests will be done:
- Blood tests to check liver function (AST and ALT). These readings can be very high with ischemia.
The aspartate aminotransferase (AST) blood test measures the level of the enzyme AST in the blood.Read Article Now Book Mark Article
- Doppler ultrasound of the blood vessels of liver.
Treatment depends on the cause. Low blood pressure and blood clots must be treated right away.
People generally recover if the illness causing hepatic ischemia can be treated. Death from liver failure due to hepatic ischemia is very rare.
Liver failure is a rare, but fatal complication.
When to Contact a Medical Professional
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Quickly treating the causes of low blood pressure may prevent hepatic ischemia.
Hauser SC. Vascular diseases of the gastrointestinal tract. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 143.
Trivedi HD. Ischemic hepatitis. In: Ferri FF, ed. Ferri's Clinical Advisor 2018. Philadelphia, PA: Elsevier; 2018: 726-726.e1.
Valla DC. Vascular diseases of the liver. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 85.
Review Date: 4/2/2018
Reviewed By: Michael M. Phillips, MD, Clinical Professor of Medicine, The George Washington University School of Medicine, Washington, DC. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.