BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuAnticonvulsant medications - barbituratesBarbiturate anticonvulsant medications includes:Phenobarbital (Luminal) Primidone (Mysoline) Mephobarbital (Mebaral) DepletionsTaking mephobarbital, primidone, or their metabolite, phenobarbital, may deplete calcium, vitamin A, vitamin B9, and vitamin D with long-term use.CalciumCalcium, along with vitamin D, keeps your bones strong and healthy.Low levels of calcium may cause:Muscle cramps Numbness or tingling in toes and feet Irregular heartbeat Depression Bone pain Spinal problems Seizures Vitamin B9 (Folic Acid)Low levels of folic acid in the body may be linked to:Anemia Heart disease Birth defects Symptoms may include:Weakness Mouth sores Swollen tongue Depression Poor growth Vitamin DVitamin D, along with calcium, keeps your bones strong and healthy.Low levels of vitamin D may cause: Increased risk of osteoporosis Softening of the bones, called rickets in children and osteomalacia in adults Fractures even on minor injury Muscle cramps Seizures Numbness or tingling in toes and feet Vitamin ALow levels of vitamin A may cause:Night blindness Rough and dry skin Itchy skin Dull hair Broken nails Increased risk of infections Editorial NoteThe information presented here covers some of the nutrients that may be affected when you take certain medicines. If you have any of these signs and symptoms, it does not always mean you have low levels of these nutrients.Factors that affect the level of nutrients are:Your medical history Diet Lifestyle How long you have been taking the medicine Please talk to your health care provider. They can best address your health care needs and see if you are at risk for low levels of any nutrients.Supporting ResearchAsiedu DK. Vitamin deficiency (Hypovitaminosis). In: Ferri FF, ed. Ferri's Clinical Advisor 2017. Philadelphia, PA: Elsevier; 2017:1359-1360.Dominiczak MH, Broom JI. Vitamins and minerals. In: Baynes JW, Dominiczak MH, eds. Medical Biochemistry. 4th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 11.Gold Standard Drug Database. Drug Monograph: Phenobarbital. 2016. www.clinicalkey.com/#!/content/drug_monograph/6-s2.0-171. Accessed July7, 2016.Gold Standard Drug Database. Drug Monograph: Primidone. 2016. www.clinicalkey.com/#!/content/drug_monograph/6-s2.0-508. Accessed July 12, 2016.Gold Standard Drug Database. Drug Monograph: Mephobarbital. 2016. www.clinicalkey.com/#!/content/drug_monograph/6-s2.0-1433. Accessed July 12, 2016.Greenbaum LA. Vitamin K deficiency. In: Kliegman RM, Stanton BF, St Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics. 20th ed. Philadelphia, PA: Elsevier; 2016:chap 53.Shenkin A, Roberts NB. Vitamins and trace elements. In: Burtis CA, Ashwood ER, Bruns DE, eds. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 5th ed. St. Louis, MO: Elsevier Saunders; 2012:chap 31.Smogorzewski MJ, Stubbs JR, Yu ASL. Disorders of calcium, magnesium, and phosphate balance. In: Skorecki K, Chertow GM, Marsden PA, Yu ASL, Taal MW, eds. Brenner and Rector's The Kidney. 10th ed. Philadelphia, PA: Elsevier; 2016:chap 19.Text only AllVideoImagesTogThe Basics Advanced Study PassionflowerSkullcapAnticonvulsant medications - valproic acid derivativesAnticonvulsant medications - miscellaneousAnticonvulsant medications - hydantoin derivativesSeizure disordersSt. John's wortKava kavaAnxietyRelated Information hide Review Date: 9/19/2016 Reviewed By: Steven D. Ehrlich, NMD, Solutions Acupuncture, a private practice specializing in complementary and alternative medicine, Phoenix, AZ. Review provided by VeriMed Healthcare Network. Also reviewed by the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. No warranty of any kind, either expressed or implied, is made as to the accuracy, reliability, timeliness, or correctness of any translations made by a third-party service of the information provided herein into any other language. © 1997- A.D.A.M., a business unit of Ebix, Inc. Any duplication or distribution of the information contained herein is strictly prohibited. © 1997- All rights reserved. A.D.A.M. content is best viewed in IE9 or above, Firefox and Google Chrome browser.Content is best viewed in IE9 or above, Firefox and Google Chrome browser.
Anticonvulsant medications - barbituratesBarbiturate anticonvulsant medications includes:Phenobarbital (Luminal) Primidone (Mysoline) Mephobarbital (Mebaral) DepletionsTaking mephobarbital, primidone, or their metabolite, phenobarbital, may deplete calcium, vitamin A, vitamin B9, and vitamin D with long-term use.CalciumCalcium, along with vitamin D, keeps your bones strong and healthy.Low levels of calcium may cause:Muscle cramps Numbness or tingling in toes and feet Irregular heartbeat Depression Bone pain Spinal problems Seizures Vitamin B9 (Folic Acid)Low levels of folic acid in the body may be linked to:Anemia Heart disease Birth defects Symptoms may include:Weakness Mouth sores Swollen tongue Depression Poor growth Vitamin DVitamin D, along with calcium, keeps your bones strong and healthy.Low levels of vitamin D may cause: Increased risk of osteoporosis Softening of the bones, called rickets in children and osteomalacia in adults Fractures even on minor injury Muscle cramps Seizures Numbness or tingling in toes and feet Vitamin ALow levels of vitamin A may cause:Night blindness Rough and dry skin Itchy skin Dull hair Broken nails Increased risk of infections Editorial NoteThe information presented here covers some of the nutrients that may be affected when you take certain medicines. If you have any of these signs and symptoms, it does not always mean you have low levels of these nutrients.Factors that affect the level of nutrients are:Your medical history Diet Lifestyle How long you have been taking the medicine Please talk to your health care provider. They can best address your health care needs and see if you are at risk for low levels of any nutrients.Supporting ResearchAsiedu DK. Vitamin deficiency (Hypovitaminosis). In: Ferri FF, ed. Ferri's Clinical Advisor 2017. Philadelphia, PA: Elsevier; 2017:1359-1360.Dominiczak MH, Broom JI. Vitamins and minerals. In: Baynes JW, Dominiczak MH, eds. Medical Biochemistry. 4th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 11.Gold Standard Drug Database. Drug Monograph: Phenobarbital. 2016. www.clinicalkey.com/#!/content/drug_monograph/6-s2.0-171. Accessed July7, 2016.Gold Standard Drug Database. Drug Monograph: Primidone. 2016. www.clinicalkey.com/#!/content/drug_monograph/6-s2.0-508. Accessed July 12, 2016.Gold Standard Drug Database. Drug Monograph: Mephobarbital. 2016. www.clinicalkey.com/#!/content/drug_monograph/6-s2.0-1433. Accessed July 12, 2016.Greenbaum LA. Vitamin K deficiency. In: Kliegman RM, Stanton BF, St Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics. 20th ed. Philadelphia, PA: Elsevier; 2016:chap 53.Shenkin A, Roberts NB. Vitamins and trace elements. In: Burtis CA, Ashwood ER, Bruns DE, eds. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. 5th ed. St. Louis, MO: Elsevier Saunders; 2012:chap 31.Smogorzewski MJ, Stubbs JR, Yu ASL. Disorders of calcium, magnesium, and phosphate balance. In: Skorecki K, Chertow GM, Marsden PA, Yu ASL, Taal MW, eds. Brenner and Rector's The Kidney. 10th ed. Philadelphia, PA: Elsevier; 2016:chap 19.