Biopsy
Tissue samplingA biopsy is the removal of a small piece of tissue for laboratory examination.
Biopsy catheter
When a small piece of heart muscle tissue is needed for examination, a heart biopsy can be performed. A catheter is carefully threaded into an artery or vein to gain access into the heart. A bioptome (catheter with jaws in its tip) is then introduced. Once the bioptome is in place, three to five small pieces of tissue from the heart muscle are removed. The test is performed routinely after heart transplantation to detect potential rejection. It may also be performed when cardiomyopathy, myocarditis, cardiac amyloidosis, or other disorders are suspected.
Biopsy catheter
illustration
Core needle biopsy of the breast
A core needle biopsy of the breast is a procedure to remove samples of tissue from a lump or suspicious area of the breast and evaluate it for breast cancer. Core needle biopsy uses a long, hollow needle to take several core samples of tissue, usually using ultrasound or mammographic guidance. The samples are then sent to a lab for analysis.
Core needle biopsy of the breast
illustration
Needle biopsy of the breast
A needle biopsy is performed under local anesthesia. Simple aspirations are performed with a small gauge needle to attempt to draw fluid from lumps that are thought to be cysts. Fine needle biopsy uses a larger needle to make multiple passes through a lump, drawing out tissue and fluid. Withdrawn fluid and tissue is further evaluated to determine if there are cancerous cells present.
Needle biopsy of the breast
illustration
Open biopsy of the breast
An open biopsy can be performed under local or general anesthesia and will leave a small scar. Prior to surgery, a radiologist often first marks the lump with a wire, making it easier for the surgeon to find.
Open biopsy of the breast
illustration
Rectal biopsy
Rectal biopsy can be used to determine the cause of blood, mucus, or pus in the stool. Rectal biopsy can also confirm findings of another test or x-rays, or take a biopsy of a growth found in the colon.
Rectal biopsy
illustration
Nasal biopsy
A nasal biopsy is a diagnostic procedure in which a small piece of tissue is removed from the mucosal lining of the nose. The biopsy is most often performed when abnormal tissue is observed during an examination of the nose, or when disorders affecting the nasal mucosal tissue are suspected.
Nasal biopsy
illustration
Oropharyngeal biopsy
Oropharyngeal biopsy is a procedure in which tissue from an abnormal growth or lesion is removed and sent to the lab for testing. Depending upon the size, a small portion or the entire lesion is removed.
Oropharyngeal biopsy
illustration
Pleural biopsy
In a pleural biopsy, a small piece of pleural tissue in the chest is removed with a needle. The biopsy may distinguish between a cancerous and noncancerous disease. It also can help to detect whether a viral, fungal or parasitic disease is present.
Pleural biopsy
illustration
Muscle biopsy
A muscle biopsy involves removal of a plug of tissue usually by a needle to be later used for examination. Sometimes more than one needle insertion may be needed to obtain a large enough specimen. If there is a patchy condition expected an open biopsy may be used. Open biopsy involves a small incision through the skin and into the muscle, so that a sample of muscle tissue can be removed from the affected area. There may be some slight bruising or bleeding at the site but the risks are minimal with the procedure.
Muscle biopsy
illustration
Sentinel node biopsy
Sentinel node biopsy is a technique which helps determine if a cancer has spread (metastasized), or is contained locally. When a cancer has been detected, often the next step is to find the lymph node closest to the tumor site and retrieve it for analysis. The concept of the "sentinel" node, or the first node to drain the area of the cancer, allows a more accurate staging of the cancer, and leaves unaffected nodes behind to continue the important job of draining fluids. The procedure involves the injection of a dye (sometimes mildly radioactive) to pinpoint the lymph node which is closest to the cancer site. Sentinel node biopsy is used to stage many kinds of cancer, including lung and skin (melanoma).
Sentinel node biopsy
illustration
Biopsy catheter
When a small piece of heart muscle tissue is needed for examination, a heart biopsy can be performed. A catheter is carefully threaded into an artery or vein to gain access into the heart. A bioptome (catheter with jaws in its tip) is then introduced. Once the bioptome is in place, three to five small pieces of tissue from the heart muscle are removed. The test is performed routinely after heart transplantation to detect potential rejection. It may also be performed when cardiomyopathy, myocarditis, cardiac amyloidosis, or other disorders are suspected.
Biopsy catheter
illustration
Core needle biopsy of the breast
A core needle biopsy of the breast is a procedure to remove samples of tissue from a lump or suspicious area of the breast and evaluate it for breast cancer. Core needle biopsy uses a long, hollow needle to take several core samples of tissue, usually using ultrasound or mammographic guidance. The samples are then sent to a lab for analysis.
Core needle biopsy of the breast
illustration
Needle biopsy of the breast
A needle biopsy is performed under local anesthesia. Simple aspirations are performed with a small gauge needle to attempt to draw fluid from lumps that are thought to be cysts. Fine needle biopsy uses a larger needle to make multiple passes through a lump, drawing out tissue and fluid. Withdrawn fluid and tissue is further evaluated to determine if there are cancerous cells present.
Needle biopsy of the breast
illustration
Open biopsy of the breast
An open biopsy can be performed under local or general anesthesia and will leave a small scar. Prior to surgery, a radiologist often first marks the lump with a wire, making it easier for the surgeon to find.
Open biopsy of the breast
illustration
Rectal biopsy
Rectal biopsy can be used to determine the cause of blood, mucus, or pus in the stool. Rectal biopsy can also confirm findings of another test or x-rays, or take a biopsy of a growth found in the colon.
Rectal biopsy
illustration
Nasal biopsy
A nasal biopsy is a diagnostic procedure in which a small piece of tissue is removed from the mucosal lining of the nose. The biopsy is most often performed when abnormal tissue is observed during an examination of the nose, or when disorders affecting the nasal mucosal tissue are suspected.
Nasal biopsy
illustration
Oropharyngeal biopsy
Oropharyngeal biopsy is a procedure in which tissue from an abnormal growth or lesion is removed and sent to the lab for testing. Depending upon the size, a small portion or the entire lesion is removed.
Oropharyngeal biopsy
illustration
Pleural biopsy
In a pleural biopsy, a small piece of pleural tissue in the chest is removed with a needle. The biopsy may distinguish between a cancerous and noncancerous disease. It also can help to detect whether a viral, fungal or parasitic disease is present.
Pleural biopsy
illustration
Muscle biopsy
A muscle biopsy involves removal of a plug of tissue usually by a needle to be later used for examination. Sometimes more than one needle insertion may be needed to obtain a large enough specimen. If there is a patchy condition expected an open biopsy may be used. Open biopsy involves a small incision through the skin and into the muscle, so that a sample of muscle tissue can be removed from the affected area. There may be some slight bruising or bleeding at the site but the risks are minimal with the procedure.
Muscle biopsy
illustration
Sentinel node biopsy
Sentinel node biopsy is a technique which helps determine if a cancer has spread (metastasized), or is contained locally. When a cancer has been detected, often the next step is to find the lymph node closest to the tumor site and retrieve it for analysis. The concept of the "sentinel" node, or the first node to drain the area of the cancer, allows a more accurate staging of the cancer, and leaves unaffected nodes behind to continue the important job of draining fluids. The procedure involves the injection of a dye (sometimes mildly radioactive) to pinpoint the lymph node which is closest to the cancer site. Sentinel node biopsy is used to stage many kinds of cancer, including lung and skin (melanoma).
Sentinel node biopsy
illustration
Biopsy
Tissue samplingA biopsy is the removal of a small piece of tissue for laboratory examination.
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Biopsy
Tissue samplingA biopsy is the removal of a small piece of tissue for laboratory examination.
Review Date: 9/28/2020
Reviewed By: Debra G. Wechter, MD, FACS, general surgery practice specializing in breast cancer, Virginia Mason Medical Center, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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