Tetanus is an infection of the nervous system with a type of bacteria that is potentially deadly, called Clostridium tetani (C tetani).
Spores of the bacterium C tetani are found in the soil, and in animal feces and mouth (gastrointestinal tract). In the spore form, C tetani can remain inactive in the soil. But it can remain infectious for more than 40 years.
A spore is a cell that certain fungi, plants (moss, ferns), and bacteria produce. Spores are involved in reproduction. Certain bacteria make spores ...Read Article Now Book Mark Article
You can get tetanus infection when the spores enter your body through an injury or wound. The spores become active bacteria that spread in the body and make a poison called tetanus toxin (also known as tetanospasmin). This poison blocks nerve signals from your spinal cord to your muscles, causing severe muscle spasms. The spasms can be so powerful that they tear the muscles or cause fractures of the spine.
If more pressure is put on a bone than it can stand, it will split or break. A break of any size is called a fracture. If the broken bone punctures...Read Article Now Book Mark Article
The time between infection and the first sign of symptoms is about 7 to 21 days. Most cases of tetanus in the United States occur in those who have not been vaccinated against the disease.
Tetanus often begins with mild spasms in the jaw muscles (lockjaw). The spasms can also affect your chest, neck, back, and abdominal muscles. Back muscle spasms often cause arching, called opisthotonos.
Abdominal rigidity is stiffness of the muscles in the belly area, which can be felt when touched or pressed.Read Article Now Book Mark Article
Opisthotonos is a condition in which a person holds their body in an abnormal position. The person is usually rigid and arches their back, with thei...Read Article Now Book Mark Article
Sometimes, the spasms affect muscles that help with breathing, which can lead to breathing problems.
Prolonged muscular action causes sudden, powerful, and painful contractions of muscle groups. This is called tetany. These are the episodes that can cause fractures and muscle tears.
Other symptoms include:
Drooling is saliva flowing outside the mouth.Read Article Now Book Mark Article
- Excessive sweating
Fever is the temporary increase in the body's temperature in response to a disease or illness. A child has a fever when the temperature is at or abov...Read Article Now Book Mark Article
- Hand or foot spasms
Hand or foot spasms
Spasms are contractions of the muscles of the hands, thumbs, feet, or toes. Spasms are usually brief, but they can be severe and painful.Read Article Now Book Mark Article
- Swallowing difficulty
- Uncontrolled urination or defecation
Exams and Tests
Your doctor will perform a physical exam and ask about your medical history. No specific lab test is available to diagnose tetanus.
Tests may be used to rule out meningitis, rabies, strychnine poisoning, and other diseases with similar symptoms.
Meningitis is an infection of the membranes covering the brain and spinal cord. This covering is called the meninges.Read Article Now Book Mark Article
Rabies is a deadly viral infection that is mainly spread by infected animals.Read Article Now Book Mark Article
Treatment may include:
- Bedrest with a calm environment (dim light, reduced noise, and stable temperature)
- Medicine to neutralize the poison (tetanus immune globulin)
- Muscle relaxers, such as diazepam
- Surgery to clean the wound and remove the source of the poison (debridement)
Breathing support with oxygen, a breathing tube, and a breathing machine may be necessary.
Without treatment, 1 out of 4 infected people die. The death rate for newborns with untreated tetanus is even higher. With proper treatment, less than 15% of infected people die.
Wounds on the head or face seem to be more dangerous than those on other parts of the body. If the person survives the acute illness, recovery is generally complete. Uncorrected episodes of hypoxia (lack of oxygen) caused by muscle spasms in the throat may lead to irreversible brain damage.
Acute means sudden. Acute symptoms appear, change, or worsen rapidly. It is the opposite of chronic.Read Article Now Book Mark Article
A bluish color to the skin or mucous membrane is usually due to a lack of oxygen in the blood. The medical term is cyanosis.Read Article Now Book Mark Article
Complications that may result from tetanus include:
- Airway obstruction
Breathing difficulty may involve:Difficult breathing Uncomfortable breathingFeeling like you are not getting enough airRead Article Now Book Mark Article
- Respiratory arrest
Breathing that stops from any cause is called apnea. Slowed breathing is called bradypnea. Labored or difficult breathing is known as dyspnea....Read Article Now Book Mark Article
- Heart failure
Heart failure is a condition in which the heart is no longer able to pump oxygen-rich blood to the rest of the body efficiently. This causes symptom...Read Article Now Book Mark Article
Pneumonia is a breathing (respiratory) condition in which there is an infection of the lung. This article covers community-acquired pneumonia (CAP). ...Read Article Now Book Mark Article
- Damage to muscles
- Brain damage due to lack of oxygen during spasms
When to Contact a Medical Professional
Contact your health care provider right away if you have an open wound, particularly if:
A cut is a break or opening in the skin. It is also called a laceration. A cut may be deep, smooth, or jagged. It may be near the surface of the s...Read Article Now Book Mark Article
- You are injured outdoors.
- The wound has been in contact with soil.
- You have not received a tetanus booster (vaccine) within 10 years or you are not sure of your vaccination status.
Contact your provider for an appointment if you have never been immunized against tetanus as an adult or child. Also contact your provider if your children have not been immunized, or if you are unsure of your tetanus immunization (vaccine) status.
Tetanus is completely preventable by being immunized (vaccinated). Immunization usually protects against tetanus infection for 10 years.
In the United States, immunizations begin in infancy with the DTaP series of shots. The DTaP vaccine is a 3-in-1 vaccine that protects against diphtheria, pertussis, and tetanus.
All content below is taken in its entirety from the Centers for Disease Control and Prevention (CDC) DTaP vaccine information statement (VIS) -- www....Read Article Now Book Mark Article
Diphtheria is an acute infection caused by the bacterium Corynebacterium diphtheriae.Read Article Now Book Mark Article
Pertussis is a highly contagious bacterial disease that causes uncontrollable, violent coughing. The coughing can make it hard to breathe. A deep "...Read Article Now Book Mark Article
Td vaccine or Tdap vaccine is used to maintain immunity in people age 7 and older. Tdap vaccine should be given once, before age 65, as a substitute for Td for those who have not had Tdap. Td boosters are recommended every 10 years starting at age 19.
All content below is taken in its entirety from the Centers for Disease Control and Prevention (CDC) Td vaccine information statement (VIS) -- www. c...Read Article Now Book Mark Article
All content below is taken in its entirety from the Centers for Disease Control (CDC) Tdap Vaccine Information Statement (VIS): www. cdc. gov/vaccine...Read Article Now Book Mark Article
Older teenagers and adults who get injuries, especially puncture-type wounds, should get a tetanus booster if it has been more than 10 years since the last booster.
If you have been injured outside or in any way that makes contact with soil likely, contact your provider about your risk of getting a tetanus infection. Injuries and wounds should be thoroughly cleaned right away. If the tissue of the wound is dying, a doctor will need to remove the tissue.
You may have heard that you can get tetanus if you are injured by a rusty nail. This is true only if the nail is dirty and has the tetanus bacteria on it. It is the dirt on the nail, not the rust that carries the risk for tetanus.
Birch TB, Bleck TP. Tetanus (Clostridium tetani). In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 244.
Simon BC, Hern HG. Wound management principles. In: Walls RM, Hockberger RS, Gausche-Hill M, eds. Rosen's Emergency Medicine: Concepts and Clinical Practice. 9th ed. Philadelphia, PA: Elsevier; 2018:chap 52.
Review Date: 11/23/2021
Reviewed By: Jatin M. Vyas, MD, PhD, Associate Professor in Medicine, Harvard Medical School; Associate in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.