BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuMyocarditis - pediatricPediatric myocarditis is inflammation of the heart muscle in an infant or young child. Causes Myocarditis is rare in young children. It is slightly more common in older children and adults. It is often worse in newborns and young infants than in children over age 2.Most cases in children are caused by a virus that reaches the heart. These can include:Influenza (flu) virus Influenza (flu)The flu (influenza) is a viral respiratory illness that causes fever, chills, runny nose, body aches, and cough. It spreads easily from person to pe...ImageRead Article Now Book Mark Article Coxsackie virus Parovirus Adenovirus SARS-CoV-2 virus (the virus that causes COVID-19)COVID-19)Coronavirus disease 2019 (COVID-19) is a respiratory illness that causes fever, coughing, and shortness of breath, but many other symptoms can occur....ImageRead Article Now Book Mark Article It may also be caused by bacterial infections such as Lyme disease.Lyme diseaseLyme disease is a bacterial infection that is spread through the bite of one of several types of ticks.ImageRead Article Now Book Mark Article Other causes of pediatric myocarditis include:Allergic reactions to certain medicines Exposure to chemicals in the environment Infections due to fungus or parasites Radiation Some diseases (autoimmune disorders) that cause inflammation throughout the body Some drugs Myocarditis following COVID-19 vaccination has been reported, but is very rare.The heart muscle may be directly damaged by the virus or the bacteria that infect it. The body's immune response can also damage the heart muscle (called the myocardium) in the process of fighting the infection. This can lead to symptoms of heart failure. Symptoms Symptoms may be mild at first and hard to detect. Sometimes in newborns and infants, symptoms may appear suddenly.Symptoms may include:Anxiety Failure to thrive or poor weight gain Failure to thriveFailure to thrive refers to children whose current weight or rate of weight gain is much lower than that of other children of similar age and sex....Read Article Now Book Mark Article Feeding difficulties Fever and other symptoms of infection Listlessness Low urine output (a sign of decreasing kidney function) Pale, cool hands and feet (a sign of poor circulation) Rapid breathing Rapid breathingA normal breathing rate for an adult at rest is 12 to 20 breaths per minute. For an infant, a normal rate is 30 to 60 breaths per minute. Tachypnea ...ImageRead Article Now Book Mark Article Rapid heart rate Symptoms in children over age 2 may also include:Belly area pain and nausea Chest pain Cough Fatigue Shortness of breath Swelling (edema) in the legs, feet, and face Exams and Tests Pediatric myocarditis can be hard to diagnose because the signs and symptoms often mimic those of other heart and lung diseases, or a bad case of the flu.The health care provider may hear a rapid heartbeat or abnormal heart sounds while listening to the child's chest with a stethoscope.A physical exam may show:Fluid in the lungs and swelling in the legs in older children. Signs of infection, including fever and rashes.A chest x-ray can show enlargement (swelling) of the heart. If the provider suspects myocarditis based on the exam and chest x-ray, an electrocardiogram may also be done to help make the diagnosis.Other tests that may be needed include:Blood cultures to check for infection Blood tests to look for antibodies against viruses or the heart muscle itself Blood tests to check liver and kidney function Complete blood count Complete blood countA complete blood count (CBC) test measures the following:The number of white blood cells (WBC count)The number of red blood cells (RBC count)The numb...ImageRead Article Now Book Mark Article Heart biopsy (the most accurate way to confirm the diagnosis, but not always needed) Special tests to check for the presence of viruses in the blood (viral PCR) Treatment There is no cure for myocarditis. The heart muscle inflammation will often go away on its own. The goal of treatment is to support heart function until the inflammation goes away. Many children with this condition are admitted to a hospital. Activity often needs to be limited while the heart is inflamed because it can strain the heart.Treatment may include:Antibiotics to fight bacterial infection Anti-inflammatory medicines called steroids to control inflammation Intravenous immunoglobulin (IVIG), a medicine made of substances (called antibodies) that the body produces to fight infection, to control the inflammatory process Mechanical support using a machine to help the heart function (in extreme cases) Medicines to treat symptoms of heart failure Medicines to treat abnormal heart rhythms Outlook (Prognosis) Recovery from myocarditis depends on the cause of the problem and the child's overall health. Most children recover completely with proper treatment. However, some may have permanent heart disease.Newborns have the highest risk for serious disease and complications (including death) due to myocarditis. In rare cases, severe damage to the heart muscle requires a heart transplant. Possible Complications Complications may include:Enlargement of the heart that leads to reduced heart function (dilated cardiomyopathy) Heart failure Heart rhythm problems When to Contact a Medical Professional Contact your child's provider if signs or symptoms of this condition occur. Prevention There is no known prevention. However, prompt testing and treatment may reduce the disease risk. Open ReferencesReferencesCenters for Disease Control and Prevention website. Safety of COVID-19 vaccines. www.cdc.gov/coronavirus/2019-ncov/vaccines/safety/safety-of-vaccines.html. Updated November 3, 2023. Accessed February 26, 2024.Knowlton KU, Anderson JL, Savoia MC, Oxman MN. Myocarditis and pericarditis. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 84.McNamara DM. Heart failure as a consequence of viral and nonviral myocarditis. In: Felker GM, Mann DL, eds. Heart Failure: A Companion to Braunwald's Heart Disease. 4th ed. Philadelphia, PA: Elsevier; 2020:chap 28.Parent JJ, Ware SM. Diseases of the myocardium. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 466.AllVideoImagesTogMyocarditis - illustration Myocarditis is inflammation and weakness of the heart muscle usually caused by a viral infection that reaches the heart, such as the influenza (flu) virus, Coxsackie virus, and adenovirus. Myocarditis can damage the heart muscle causing it to become thick and swollen. This leads to symptoms of heart failure. Myocarditis may also occur during or after other viral or bacterial infections such as polio, rubella, Lyme disease, and others.MyocarditisillustrationMyocarditis - illustration Myocarditis is inflammation and weakness of the heart muscle usually caused by a viral infection that reaches the heart, such as the influenza (flu) virus, Coxsackie virus, and adenovirus. Myocarditis can damage the heart muscle causing it to become thick and swollen. This leads to symptoms of heart failure. Myocarditis may also occur during or after other viral or bacterial infections such as polio, rubella, Lyme disease, and others.MyocarditisillustrationRelated Information Review Date: 2/17/2024 Reviewed By: Charles I. Schwartz, MD, FAAP, Clinical Assistant Professor of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, General Pediatrician at PennCare for Kids, Phoenixville, PA. Also reviewed by David C. 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Myocarditis - pediatricPediatric myocarditis is inflammation of the heart muscle in an infant or young child. Causes Myocarditis is rare in young children. It is slightly more common in older children and adults. It is often worse in newborns and young infants than in children over age 2.Most cases in children are caused by a virus that reaches the heart. These can include:Influenza (flu) virus Influenza (flu)The flu (influenza) is a viral respiratory illness that causes fever, chills, runny nose, body aches, and cough. It spreads easily from person to pe...ImageRead Article Now Book Mark Article Coxsackie virus Parovirus Adenovirus SARS-CoV-2 virus (the virus that causes COVID-19)COVID-19)Coronavirus disease 2019 (COVID-19) is a respiratory illness that causes fever, coughing, and shortness of breath, but many other symptoms can occur....ImageRead Article Now Book Mark Article It may also be caused by bacterial infections such as Lyme disease.Lyme diseaseLyme disease is a bacterial infection that is spread through the bite of one of several types of ticks.ImageRead Article Now Book Mark Article Other causes of pediatric myocarditis include:Allergic reactions to certain medicines Exposure to chemicals in the environment Infections due to fungus or parasites Radiation Some diseases (autoimmune disorders) that cause inflammation throughout the body Some drugs Myocarditis following COVID-19 vaccination has been reported, but is very rare.The heart muscle may be directly damaged by the virus or the bacteria that infect it. The body's immune response can also damage the heart muscle (called the myocardium) in the process of fighting the infection. This can lead to symptoms of heart failure. Symptoms Symptoms may be mild at first and hard to detect. Sometimes in newborns and infants, symptoms may appear suddenly.Symptoms may include:Anxiety Failure to thrive or poor weight gain Failure to thriveFailure to thrive refers to children whose current weight or rate of weight gain is much lower than that of other children of similar age and sex....Read Article Now Book Mark Article Feeding difficulties Fever and other symptoms of infection Listlessness Low urine output (a sign of decreasing kidney function) Pale, cool hands and feet (a sign of poor circulation) Rapid breathing Rapid breathingA normal breathing rate for an adult at rest is 12 to 20 breaths per minute. For an infant, a normal rate is 30 to 60 breaths per minute. Tachypnea ...ImageRead Article Now Book Mark Article Rapid heart rate Symptoms in children over age 2 may also include:Belly area pain and nausea Chest pain Cough Fatigue Shortness of breath Swelling (edema) in the legs, feet, and face Exams and Tests Pediatric myocarditis can be hard to diagnose because the signs and symptoms often mimic those of other heart and lung diseases, or a bad case of the flu.The health care provider may hear a rapid heartbeat or abnormal heart sounds while listening to the child's chest with a stethoscope.A physical exam may show:Fluid in the lungs and swelling in the legs in older children. Signs of infection, including fever and rashes.A chest x-ray can show enlargement (swelling) of the heart. If the provider suspects myocarditis based on the exam and chest x-ray, an electrocardiogram may also be done to help make the diagnosis.Other tests that may be needed include:Blood cultures to check for infection Blood tests to look for antibodies against viruses or the heart muscle itself Blood tests to check liver and kidney function Complete blood count Complete blood countA complete blood count (CBC) test measures the following:The number of white blood cells (WBC count)The number of red blood cells (RBC count)The numb...ImageRead Article Now Book Mark Article Heart biopsy (the most accurate way to confirm the diagnosis, but not always needed) Special tests to check for the presence of viruses in the blood (viral PCR) Treatment There is no cure for myocarditis. The heart muscle inflammation will often go away on its own. The goal of treatment is to support heart function until the inflammation goes away. Many children with this condition are admitted to a hospital. Activity often needs to be limited while the heart is inflamed because it can strain the heart.Treatment may include:Antibiotics to fight bacterial infection Anti-inflammatory medicines called steroids to control inflammation Intravenous immunoglobulin (IVIG), a medicine made of substances (called antibodies) that the body produces to fight infection, to control the inflammatory process Mechanical support using a machine to help the heart function (in extreme cases) Medicines to treat symptoms of heart failure Medicines to treat abnormal heart rhythms Outlook (Prognosis) Recovery from myocarditis depends on the cause of the problem and the child's overall health. Most children recover completely with proper treatment. However, some may have permanent heart disease.Newborns have the highest risk for serious disease and complications (including death) due to myocarditis. In rare cases, severe damage to the heart muscle requires a heart transplant. Possible Complications Complications may include:Enlargement of the heart that leads to reduced heart function (dilated cardiomyopathy) Heart failure Heart rhythm problems When to Contact a Medical Professional Contact your child's provider if signs or symptoms of this condition occur. Prevention There is no known prevention. However, prompt testing and treatment may reduce the disease risk. Open ReferencesReferencesCenters for Disease Control and Prevention website. Safety of COVID-19 vaccines. www.cdc.gov/coronavirus/2019-ncov/vaccines/safety/safety-of-vaccines.html. Updated November 3, 2023. Accessed February 26, 2024.Knowlton KU, Anderson JL, Savoia MC, Oxman MN. Myocarditis and pericarditis. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 84.McNamara DM. Heart failure as a consequence of viral and nonviral myocarditis. In: Felker GM, Mann DL, eds. Heart Failure: A Companion to Braunwald's Heart Disease. 4th ed. Philadelphia, PA: Elsevier; 2020:chap 28.Parent JJ, Ware SM. Diseases of the myocardium. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 466.