BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuDrugs that may cause erection problemsImpotence caused by medicines; Drug-induced erectile dysfunction; Prescription medicines and impotence Information Many medicines and recreational drugs can affect a man's sexual arousal and sexual performance. What causes erection problems in one man may not affect another man. Erection problemsAn erection problem occurs when a man cannot get or keep an erection that is firm enough for intercourse. You may not be able to get an erection at ...Read Article Now Book Mark Article Talk to your health care provider if you think that a drug is having a negative effect on your sexual performance. Never stop taking any medicine without first talking to your provider. Some medicines may lead to life-threatening reactions if you do not take care when stopping or changing them.The following is a list of some medicines and drugs that may cause erectile dysfunction (ED) in men. There may be additional drugs other than those on this list that can cause erection difficulties.Antidepressants and other medicines for mental health conditions:Amitriptyline (Elavil) Amoxapine (Asendin) Buspirone (Buspar) Chlordiazepoxide (Librium) Chlorpromazine (Thorazine) Clomipramine (Anafranil) Clorazepate (Tranxene) Desipramine (Norpramin) Diazepam (Valium) Doxepin (Sinequan) Fluoxetine (Prozac) Fluphenazine (Prolixin) Imipramine (Tofranil) Isocarboxazid (Marplan) Lorazepam (Ativan) Meprobamate (Equanil) Mesoridazine (Serentil) Nortriptyline (Pamelor) Oxazepam (Serax) Phenelzine (Nardil) Phenytoin (Dilantin) Sertraline (Zoloft) Thioridazine (Mellaril) Thiothixene (Navane) Tranylcypromine (Parnate) Trifluoperazine (Stelazine) Antihistamine medicines (certain classes of antihistamines are also used to treat heartburn):Cimetidine (Tagamet) Dimenhydrinate (Dramamine) Diphenhydramine (Benadryl) Hydroxyzine (Vistaril) Meclizine (Antivert) Nizatidine (Axid) Promethazine (Phenergan) Ranitidine (Zantac) High blood pressure medicines and diuretics (water pills):Atenolol (Tenormin) Bethanidine Bumetanide (Bumex) Captopril (Capoten) Chlorothiazide (Diuril) Chlorthalidone (Hygroton) Clonidine (Catapres) Enalapril (Vasotec) Furosemide (Lasix) Guanabenz (Wytensin) Guanethidine (Ismelin) Guanfacine (Tenex) Haloperidol (Haldol) Hydralazine (Apresoline) Hydrochlorothiazide (Esidrix) Labetalol (Normodyne) Methyldopa (Aldomet) Metoprolol (Lopressor) Nifedipine (Adalat, Procardia) Phenoxybenzamine (Dibenzyline) Phentolamine (Regitine) Prazosin (Minipress) Propranolol (Inderal) Reserpine (Serpasil) Spironolactone (Aldactone) Triamterene (Maxzide) Verapamil (Calan) Thiazides are the most common cause of erectile dysfunction among the high blood pressure medicines. The next most common cause is beta blockers. Alpha blockers tend to be less likely to cause this problem.Parkinson disease medicines:Benztropine (Cogentin) Biperiden (Akineton) Bromocriptine (Parlodel) Levodopa (Sinemet) Procyclidine (Kemadrin) Trihexyphenidyl (Artane) Chemotherapy and hormonal medicines:ChemotherapyThe term chemotherapy is used to describe cancer-killing drugs. Chemotherapy may be used to:Cure the cancerShrink the cancerPrevent the cancer from ...Read Article Now Book Mark Article Antiandrogens (Casodex, Flutamide, Nilutamide) Busulfan (Myleran) Cyclophosphamide (Cytoxan) Ketoconazole LHRH agonists (Lupron, Zoladex) LHRH antagonist (Firmagon)Other medicines:Aminocaproic acid (Amicar) Atropine Clofibrate (Atromid-S) Cyclobenzaprine (Flexeril) Cyproterone Digoxin (Lanoxin) Disopyramide (Norpace) Dutasteride (Avodart) Estrogen Finasteride (Propecia, Proscar) Furazolidone (Furoxone) H2 blockers (Tagamet, Zantac, Pepcid) Indomethacin (Indocin) Lipid-lowering agents Licorice Metoclopramide (Reglan) Nonsteroidal anti-inflammatory drugs (NSAIDs, ibuprofen, etc.) Orphenadrine (Norflex) Prochlorperazine (Compazine) Pseudoephedrine (Sudafed) Sumatriptan (Imitrex) Opiate analgesics (painkillers):Codeine Fentanyl (Innovar) Hydromorphone (Dilaudid) Meperidine (Demerol) Methadone Morphine Oxycodone (Oxycontin, Percodan) Recreational drugs:Alcohol Amphetamines Barbiturates Cocaine CocaineA toxicology screen refers to various tests that determine the type and approximate amount of legal and illegal drugs a person has taken by measuring...Read Article Now Book Mark Article Marijuana MarijuanaSubstance use is the continued use of alcohol, illegal drugs, or the misuse of prescription or over-the-counter medicines with negative consequences....Read Article Now Book Mark Article Heroin and other opioids Nicotine Open ReferencesReferencesBurnett AL, Ramasamy R. Evaluation and management of erectile dysfunction. In: Partin AW, Dmochowski RR, Kavoussi LR, Peters CA, eds. Campbell-Walsh-Wein Urology. 12th ed. Philadelphia, PA: Elsevier; 2021:chap 69.Liu JL, Bivalacqua TJ. Erectile dysfunction. In: Sidawy AN, Perler BA, eds. Rutherford's Vascular Surgery and Endovascular Therapy. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 191.Waller DG. Erectile dysfunction. In: Waller DG, ed. Medical Pharmacology and Therapeutics. 6th ed. Philadelphia, PA: Elsevier Limited; 2022:chap 16.AllVideoImagesTogSelf Care Vacuum erectile devices for erection problemsErection problems - aftercareRelated Information Erectile dysfunction - InDepth(In-Depth) Review Date: 1/1/2023 Reviewed By: Kelly L. Stratton, MD, FACS, Associate Professor, Department of Urology, University of Oklahoma Health Sciences Center, Oklahoma City, OK. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. 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Drugs that may cause erection problemsImpotence caused by medicines; Drug-induced erectile dysfunction; Prescription medicines and impotence Information Many medicines and recreational drugs can affect a man's sexual arousal and sexual performance. What causes erection problems in one man may not affect another man. Erection problemsAn erection problem occurs when a man cannot get or keep an erection that is firm enough for intercourse. You may not be able to get an erection at ...Read Article Now Book Mark Article Talk to your health care provider if you think that a drug is having a negative effect on your sexual performance. Never stop taking any medicine without first talking to your provider. Some medicines may lead to life-threatening reactions if you do not take care when stopping or changing them.The following is a list of some medicines and drugs that may cause erectile dysfunction (ED) in men. There may be additional drugs other than those on this list that can cause erection difficulties.Antidepressants and other medicines for mental health conditions:Amitriptyline (Elavil) Amoxapine (Asendin) Buspirone (Buspar) Chlordiazepoxide (Librium) Chlorpromazine (Thorazine) Clomipramine (Anafranil) Clorazepate (Tranxene) Desipramine (Norpramin) Diazepam (Valium) Doxepin (Sinequan) Fluoxetine (Prozac) Fluphenazine (Prolixin) Imipramine (Tofranil) Isocarboxazid (Marplan) Lorazepam (Ativan) Meprobamate (Equanil) Mesoridazine (Serentil) Nortriptyline (Pamelor) Oxazepam (Serax) Phenelzine (Nardil) Phenytoin (Dilantin) Sertraline (Zoloft) Thioridazine (Mellaril) Thiothixene (Navane) Tranylcypromine (Parnate) Trifluoperazine (Stelazine) Antihistamine medicines (certain classes of antihistamines are also used to treat heartburn):Cimetidine (Tagamet) Dimenhydrinate (Dramamine) Diphenhydramine (Benadryl) Hydroxyzine (Vistaril) Meclizine (Antivert) Nizatidine (Axid) Promethazine (Phenergan) Ranitidine (Zantac) High blood pressure medicines and diuretics (water pills):Atenolol (Tenormin) Bethanidine Bumetanide (Bumex) Captopril (Capoten) Chlorothiazide (Diuril) Chlorthalidone (Hygroton) Clonidine (Catapres) Enalapril (Vasotec) Furosemide (Lasix) Guanabenz (Wytensin) Guanethidine (Ismelin) Guanfacine (Tenex) Haloperidol (Haldol) Hydralazine (Apresoline) Hydrochlorothiazide (Esidrix) Labetalol (Normodyne) Methyldopa (Aldomet) Metoprolol (Lopressor) Nifedipine (Adalat, Procardia) Phenoxybenzamine (Dibenzyline) Phentolamine (Regitine) Prazosin (Minipress) Propranolol (Inderal) Reserpine (Serpasil) Spironolactone (Aldactone) Triamterene (Maxzide) Verapamil (Calan) Thiazides are the most common cause of erectile dysfunction among the high blood pressure medicines. The next most common cause is beta blockers. Alpha blockers tend to be less likely to cause this problem.Parkinson disease medicines:Benztropine (Cogentin) Biperiden (Akineton) Bromocriptine (Parlodel) Levodopa (Sinemet) Procyclidine (Kemadrin) Trihexyphenidyl (Artane) Chemotherapy and hormonal medicines:ChemotherapyThe term chemotherapy is used to describe cancer-killing drugs. Chemotherapy may be used to:Cure the cancerShrink the cancerPrevent the cancer from ...Read Article Now Book Mark Article Antiandrogens (Casodex, Flutamide, Nilutamide) Busulfan (Myleran) Cyclophosphamide (Cytoxan) Ketoconazole LHRH agonists (Lupron, Zoladex) LHRH antagonist (Firmagon)Other medicines:Aminocaproic acid (Amicar) Atropine Clofibrate (Atromid-S) Cyclobenzaprine (Flexeril) Cyproterone Digoxin (Lanoxin) Disopyramide (Norpace) Dutasteride (Avodart) Estrogen Finasteride (Propecia, Proscar) Furazolidone (Furoxone) H2 blockers (Tagamet, Zantac, Pepcid) Indomethacin (Indocin) Lipid-lowering agents Licorice Metoclopramide (Reglan) Nonsteroidal anti-inflammatory drugs (NSAIDs, ibuprofen, etc.) Orphenadrine (Norflex) Prochlorperazine (Compazine) Pseudoephedrine (Sudafed) Sumatriptan (Imitrex) Opiate analgesics (painkillers):Codeine Fentanyl (Innovar) Hydromorphone (Dilaudid) Meperidine (Demerol) Methadone Morphine Oxycodone (Oxycontin, Percodan) Recreational drugs:Alcohol Amphetamines Barbiturates Cocaine CocaineA toxicology screen refers to various tests that determine the type and approximate amount of legal and illegal drugs a person has taken by measuring...Read Article Now Book Mark Article Marijuana MarijuanaSubstance use is the continued use of alcohol, illegal drugs, or the misuse of prescription or over-the-counter medicines with negative consequences....Read Article Now Book Mark Article Heroin and other opioids Nicotine Open ReferencesReferencesBurnett AL, Ramasamy R. Evaluation and management of erectile dysfunction. In: Partin AW, Dmochowski RR, Kavoussi LR, Peters CA, eds. Campbell-Walsh-Wein Urology. 12th ed. Philadelphia, PA: Elsevier; 2021:chap 69.Liu JL, Bivalacqua TJ. Erectile dysfunction. In: Sidawy AN, Perler BA, eds. Rutherford's Vascular Surgery and Endovascular Therapy. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 191.Waller DG. Erectile dysfunction. In: Waller DG, ed. Medical Pharmacology and Therapeutics. 6th ed. Philadelphia, PA: Elsevier Limited; 2022:chap 16.