BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuMethylmalonic acid blood testThe methylmalonic acid blood test measures the amount of methylmalonic acid in the blood. How the Test is Performed A blood sample is needed.Blood sample is neededVenipuncture is the collection of blood from a vein. It is most often done for laboratory testing.ImageRead Article Now Book Mark Article How to Prepare for the Test No special preparation is necessary. How the Test will Feel When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterwards, there may be some throbbing or slight bruising. This soon goes away. Why the Test is Performed Methylmalonic acid is a substance produced when proteins, called amino acids, in the body break down.Your health care provider may order this test if there are signs of certain genetic disorders, such as methylmalonic acidemia. Testing for this disorder is often done as part of a newborn screening exam.Methylmalonic acidemiaMethylmalonic acidemia is a disorder in which the body cannot break down certain proteins and fats. The result is a buildup of a substance called me...Read Article Now Book Mark Article Newborn screening examNewborn screening tests look for developmental, genetic, and metabolic disorders in the newborn baby. This allows steps to be taken before symptoms ...Read Article Now Book Mark Article This test may also be done with other tests to check for a vitamin B12 deficiency.Vitamin B12 deficiencyAnemia is a condition in which the body does not have enough healthy red blood cells. Red blood cells provide oxygen to body tissues. There are man...ImageRead Article Now Book Mark Article Normal Results Normal values are 0.07 to 0.27 micromoles per liter.Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific test results. What Abnormal Results Mean A higher than normal value may be due to vitamin B12 deficiency or methylmalonic acidemia. Risks There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.Other risks associated with having blood drawn are slight, but may include:Fainting or feeling lightheaded Multiple punctures to locate veins Hematoma (blood buildup under the skin) Excessive bleeding Infection (a slight risk any time the skin is broken)Open ReferencesReferencesAntony AC. Megaloblastic anemias. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 8th ed. Philadelphia, PA: Elsevier; 2023:chap 40.Elghetany MT, Banki K. Erythrocytic disorders. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 33.AllVideoImagesTogBlood test - illustration Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.Blood testillustrationBlood test - illustration Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.Blood testillustrationA Closer Look Anemia - InDepth(In-Depth) Tests for Methylmalonic acid blood test Methylmalonic acid blood testVitamin B12 levelRelated Information Methylmalonic acidemia(Condition) Review Date: 11/19/2023 Reviewed By: Jacob Berman, MD, MPH, Clinical Assistant Professor of Medicine, Division of General Internal Medicine, University of Washington School of Medicine, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. 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Methylmalonic acid blood testThe methylmalonic acid blood test measures the amount of methylmalonic acid in the blood. How the Test is Performed A blood sample is needed.Blood sample is neededVenipuncture is the collection of blood from a vein. It is most often done for laboratory testing.ImageRead Article Now Book Mark Article How to Prepare for the Test No special preparation is necessary. How the Test will Feel When the needle is inserted to draw blood, some people feel moderate pain. Others feel only a prick or stinging. Afterwards, there may be some throbbing or slight bruising. This soon goes away. Why the Test is Performed Methylmalonic acid is a substance produced when proteins, called amino acids, in the body break down.Your health care provider may order this test if there are signs of certain genetic disorders, such as methylmalonic acidemia. Testing for this disorder is often done as part of a newborn screening exam.Methylmalonic acidemiaMethylmalonic acidemia is a disorder in which the body cannot break down certain proteins and fats. The result is a buildup of a substance called me...Read Article Now Book Mark Article Newborn screening examNewborn screening tests look for developmental, genetic, and metabolic disorders in the newborn baby. This allows steps to be taken before symptoms ...Read Article Now Book Mark Article This test may also be done with other tests to check for a vitamin B12 deficiency.Vitamin B12 deficiencyAnemia is a condition in which the body does not have enough healthy red blood cells. Red blood cells provide oxygen to body tissues. There are man...ImageRead Article Now Book Mark Article Normal Results Normal values are 0.07 to 0.27 micromoles per liter.Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific test results. What Abnormal Results Mean A higher than normal value may be due to vitamin B12 deficiency or methylmalonic acidemia. Risks There is little risk involved with having your blood taken. Veins and arteries vary in size from one person to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.Other risks associated with having blood drawn are slight, but may include:Fainting or feeling lightheaded Multiple punctures to locate veins Hematoma (blood buildup under the skin) Excessive bleeding Infection (a slight risk any time the skin is broken)Open ReferencesReferencesAntony AC. Megaloblastic anemias. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice. 8th ed. Philadelphia, PA: Elsevier; 2023:chap 40.Elghetany MT, Banki K. Erythrocytic disorders. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Philadelphia, PA: Elsevier; 2022:chap 33.