BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuPlasma amino acidsAmino acids blood testPlasma amino acids is a screening test, usually done on infants that looks at the amounts of amino acids in the blood. Amino acids are the building blocks for proteins in the body.Amino acidsAmino acids are molecules that combine to form proteins. Amino acids and proteins are the building blocks of life. When proteins are digested or bro...ImageRead Article Now Book Mark Article How the Test is Performed Most of the time, blood is drawn from a vein located on the inside of the elbow or the back of the hand.In infants or young children, a sharp tool called a lancet may be used to puncture the skin.The blood collects in a small glass tube called a pipette, or onto a slide or test strip. A bandage is put over the spot to stop any bleeding.The blood sample is sent to a lab. There are several types of methods used to determine the individual amino acid levels in the blood. How to Prepare for the Test The person having the test may be asked not to eat 3 or more hours before the test. Check with your child's health care provider for specific advice. How the Test will Feel There might be slight pain or a sting when the needle is inserted. You may also feel some throbbing at the site after the blood is drawn. The needle stick will probably cause an infant or child to cry. Why the Test is Performed This test is done to measure the level of amino acids in the blood.An increased level of a particular amino acid shows that there is a problem with the body's ability to break down (metabolize) that amino acid.The test may also be used to look for decreased levels of amino acids in the blood.Increased or decreased levels of amino acids in the blood may occur with fevers, inadequate nutrition, and certain medical conditions. Normal Results All measurements are in micromoles per liter (µmol/L). Normal values may vary between different laboratories. Talk to your health care provider about your specific test results.Alanine:Children: 200 to 450 Adults: 230 to 510Alpha-aminoadipic acid:Children: not detected Adults: not detectedAlpha-amino-N-butyric acid:Children: 8 to 37 Adults: 15 to 41Arginine:Children: 44 to 120 Adults: 13 to 64Asparagine:Children: 15 to 40 Adults: 45 to 130Aspartic acid:Children: 0 to 26 Adults: 0 to 6Beta-alanine:Children: 0 to 49 Adults: 0 to 29Beta-amino-isobutyric acid:Children: not detected Adults: not detectedCarnosine:Children: not detected Adults: not detectedCitrulline:Children: 16 to 32 Adults: 16 to 55Cystine:Children: 19 to 47 Adults: 30 to 65Glutamic acid:Children: 32 to 140 Adults: 18 to 98Glutamine:Children: 420 to 730 Adults: 390 to 650Glycine:Children: 110 to 240 Adults: 170 to 330Histidine:Children: 68 to 120 Adults: 26 to 120Hydroxyproline:Children: 0 to 5 Adults: not detectedIsoleucine:Children: 37 to 140 Adults: 42 to 100 Leucine:Children: 70 to 170 Adults: 66 to 170Lysine:Children: 120 to 290 Adults: 150 to 220Methionine:Children: 13 to 30 Adults: 16 to 301-methylhistidine:Children: not detected Adults: not detected3-methylhistidine:Children: 0 to 52 Adults: 0 to 64Ornithine:Children: 44 to 90 Adults: 27 to 80 Phenylalanine:Children: 26 to 86 Adults: 41 to 68Phosphoserine:Children: 0 to 12 Adults: 0 to 12Phosphoethanolamine:Children: 0 to 12 Adults: 0 to 55Proline:Children: 130 to 290 Adults: 110 to 360Serine:Children: 93 to 150 Adults: 56 to 140 Taurine:Children: 11 to 120 Adults: 45 to 130Threonine:Children: 67 to 150 Adults: 92 to 240Tyrosine:Children: 26 to 110 Adults: 45 to 74Valine:Children: 160 to 350 Adults: 150 to 310The examples above show the common measurements for results for these tests. Some laboratories use different measurements or may test different specimens. What Abnormal Results Mean An increase in the total level of amino acids in the blood may be due to:Eclampsia Inborn error of metabolism Fructose intolerance Ketoacidosis (from diabetes) Kidney failure Reye syndrome Laboratory errorA decrease in the total level of amino acids in the blood may be due to:Adrenal cortical hyperfunction Fever Hartnup disease Inborn error of metabolism Huntington chorea Malnutrition Nephrotic syndrome Phlebotomus fever Rheumatoid arthritis Laboratory errorHigh or low amounts of individual plasma amino acids must be considered with other information. Abnormal results may be due to diet, hereditary problems, or effects of a medicine. Considerations Screening infants for increased levels of amino acids can help detect problems with metabolism. Early treatment for these conditions may prevent complications in the future.Open ReferencesReferencesDietzen DJ, Vieira Willrich MA. Amino acids, peptides, and proteins. In: Rifai N, Chiu RWK, Young I, Burnham C-A D, Wittwer CT, eds. Tietz Textbook of Laboratory Medicine. 7th ed. St Louis, MO: Elsevier; 2023:chap 31.Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM. Defects in metabolism of amino acids. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 103.Riley RS, McPherson RA. Basic examination of urine. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Elsevier; 2022:chap 29.AllVideoImagesTogAmino acids - illustration Amino acids are either essential, which must be supplied by food, or nonessential, which are made in the body.Amino acidsillustrationAmino acids - illustration Amino acids are either essential, which must be supplied by food, or nonessential, which are made in the body.Amino acidsillustration Tests for Plasma amino acids Plasma amino acidsRelated Information Metabolism(Special Topic)Intellectual disability(Condition)Chronic kidney disease(Condition)Acute kidney failure(Condition)Eclampsia(Condition)Reye syndrome(Condition)Diabetic ketoacidosis(Condition)Diabetes(Condition)Rheumatoid arthritis(Condition)Huntington disease(Condition)Diabetes - type 1 - InDepth(In-Depth)Rheumatoid arthritis - InDepth(In-Depth) Review Date: 4/24/2023 Reviewed By: Anna C. Edens Hurst, MD, MS, Associate Professor in Medical Genetics, The University of Alabama at Birmingham, Birmingham, AL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. No warranty of any kind, either expressed or implied, is made as to the accuracy, reliability, timeliness, or correctness of any translations made by a third-party service of the information provided herein into any other language. © 1997- A.D.A.M., a business unit of Ebix, Inc. Any duplication or distribution of the information contained herein is strictly prohibited. © 1997- All rights reserved. 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Plasma amino acidsAmino acids blood testPlasma amino acids is a screening test, usually done on infants that looks at the amounts of amino acids in the blood. Amino acids are the building blocks for proteins in the body.Amino acidsAmino acids are molecules that combine to form proteins. Amino acids and proteins are the building blocks of life. When proteins are digested or bro...ImageRead Article Now Book Mark Article How the Test is Performed Most of the time, blood is drawn from a vein located on the inside of the elbow or the back of the hand.In infants or young children, a sharp tool called a lancet may be used to puncture the skin.The blood collects in a small glass tube called a pipette, or onto a slide or test strip. A bandage is put over the spot to stop any bleeding.The blood sample is sent to a lab. There are several types of methods used to determine the individual amino acid levels in the blood. How to Prepare for the Test The person having the test may be asked not to eat 3 or more hours before the test. Check with your child's health care provider for specific advice. How the Test will Feel There might be slight pain or a sting when the needle is inserted. You may also feel some throbbing at the site after the blood is drawn. The needle stick will probably cause an infant or child to cry. Why the Test is Performed This test is done to measure the level of amino acids in the blood.An increased level of a particular amino acid shows that there is a problem with the body's ability to break down (metabolize) that amino acid.The test may also be used to look for decreased levels of amino acids in the blood.Increased or decreased levels of amino acids in the blood may occur with fevers, inadequate nutrition, and certain medical conditions. Normal Results All measurements are in micromoles per liter (µmol/L). Normal values may vary between different laboratories. Talk to your health care provider about your specific test results.Alanine:Children: 200 to 450 Adults: 230 to 510Alpha-aminoadipic acid:Children: not detected Adults: not detectedAlpha-amino-N-butyric acid:Children: 8 to 37 Adults: 15 to 41Arginine:Children: 44 to 120 Adults: 13 to 64Asparagine:Children: 15 to 40 Adults: 45 to 130Aspartic acid:Children: 0 to 26 Adults: 0 to 6Beta-alanine:Children: 0 to 49 Adults: 0 to 29Beta-amino-isobutyric acid:Children: not detected Adults: not detectedCarnosine:Children: not detected Adults: not detectedCitrulline:Children: 16 to 32 Adults: 16 to 55Cystine:Children: 19 to 47 Adults: 30 to 65Glutamic acid:Children: 32 to 140 Adults: 18 to 98Glutamine:Children: 420 to 730 Adults: 390 to 650Glycine:Children: 110 to 240 Adults: 170 to 330Histidine:Children: 68 to 120 Adults: 26 to 120Hydroxyproline:Children: 0 to 5 Adults: not detectedIsoleucine:Children: 37 to 140 Adults: 42 to 100 Leucine:Children: 70 to 170 Adults: 66 to 170Lysine:Children: 120 to 290 Adults: 150 to 220Methionine:Children: 13 to 30 Adults: 16 to 301-methylhistidine:Children: not detected Adults: not detected3-methylhistidine:Children: 0 to 52 Adults: 0 to 64Ornithine:Children: 44 to 90 Adults: 27 to 80 Phenylalanine:Children: 26 to 86 Adults: 41 to 68Phosphoserine:Children: 0 to 12 Adults: 0 to 12Phosphoethanolamine:Children: 0 to 12 Adults: 0 to 55Proline:Children: 130 to 290 Adults: 110 to 360Serine:Children: 93 to 150 Adults: 56 to 140 Taurine:Children: 11 to 120 Adults: 45 to 130Threonine:Children: 67 to 150 Adults: 92 to 240Tyrosine:Children: 26 to 110 Adults: 45 to 74Valine:Children: 160 to 350 Adults: 150 to 310The examples above show the common measurements for results for these tests. Some laboratories use different measurements or may test different specimens. What Abnormal Results Mean An increase in the total level of amino acids in the blood may be due to:Eclampsia Inborn error of metabolism Fructose intolerance Ketoacidosis (from diabetes) Kidney failure Reye syndrome Laboratory errorA decrease in the total level of amino acids in the blood may be due to:Adrenal cortical hyperfunction Fever Hartnup disease Inborn error of metabolism Huntington chorea Malnutrition Nephrotic syndrome Phlebotomus fever Rheumatoid arthritis Laboratory errorHigh or low amounts of individual plasma amino acids must be considered with other information. Abnormal results may be due to diet, hereditary problems, or effects of a medicine. Considerations Screening infants for increased levels of amino acids can help detect problems with metabolism. Early treatment for these conditions may prevent complications in the future.Open ReferencesReferencesDietzen DJ, Vieira Willrich MA. Amino acids, peptides, and proteins. In: Rifai N, Chiu RWK, Young I, Burnham C-A D, Wittwer CT, eds. Tietz Textbook of Laboratory Medicine. 7th ed. St Louis, MO: Elsevier; 2023:chap 31.Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM. Defects in metabolism of amino acids. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 103.Riley RS, McPherson RA. Basic examination of urine. In: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis and Management by Laboratory Methods. 24th ed. Elsevier; 2022:chap 29.