BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuLomotil overdoseDiphenoxylate with atropine overdose; Atropine with diphenoxylate overdoseLomotil is a prescription medicine used to treat diarrhea. Lomotil overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose.This article is for information only. DO NOT use it to treat or manage an actual overdose. If you or someone you are with has an overdose, call your local emergency number (such as 911), or your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.OverdoseAn overdose is when you take more than the recommended amount of something, often a medicine or drug. An overdose may result in serious, harmful sym...Read Article Now Book Mark Article Poisonous Ingredient Lomotil contains two medicines that can be harmful in large amounts. They are:Atropine Diphenoxylate (an opioid) Where Found Medicines with these names contain atropine and diphenoxylate:Lofene Logen Lomanate Lomotil LonoxOther medicines may also contain atropine and diphenoxylate. Symptoms Symptoms of a Lomotil overdose include:Slow breathing, or breathing stops Pounding heartbeat (palpitations) Pounding heartbeatPalpitations are feelings or sensations that your heart is pounding or racing. They can be felt in your chest, throat, or neck. You may:Have an unpl...Read Article Now Book Mark Article Rapid heartbeat Rapid heartbeatPalpitations are feelings or sensations that your heart is pounding or racing. They can be felt in your chest, throat, or neck. You may:Have an unpl...Read Article Now Book Mark Article Slowdown or stoppage of the bowels Slowdown or stoppage of the bowelsIntestinal obstruction is a partial or complete blockage of the bowel. The contents of the intestine cannot pass through it.Read Article Now Book Mark Article Coma (decreased level of consciousness, lack of responsiveness) ComaDecreased alertness is a state of reduced awareness and is often a serious condition. A coma is the most severe state of decreased alertness from whi...Read Article Now Book Mark Article Constipation ConstipationConstipation in infants and children means they have hard stools or have problems passing stools. A child may have pain while passing stools or may ...Read Article Now Book Mark Article Seizures (convulsions) SeizuresA seizure is the physical changes in behavior that occurs during an episode of specific types of abnormal electrical activity in the brain. The term ...Read Article Now Book Mark Article Drowsiness DrowsinessDrowsiness refers to feeling more sleepy than normal during the day. People who are drowsy may fall asleep when they do not want to or at times whic...Read Article Now Book Mark Article Dry mucous membranes in the mouth Eye changes in pupil size (may be small, normal-sized, or large) Eyes move quickly from side to side Flushed skin Flushed skinSkin blushing or flushing is a sudden reddening of the face, neck, or upper chest due to increased blood flow.Read Article Now Book Mark Article Hallucinations (seeing or hearing things that aren't there) HallucinationsHallucinations involve sensing things such as visions, sounds, or smells that seem real but are not. These things are created by the mind.Read Article Now Book Mark Article Restlessness Urination difficulty VomitingNote: Symptoms may take up to 12 hours to appear. Home Care Seek medical help right away. Do not make a person throw up unless poison control or a health care provider tells you to. Before Calling Emergency Have this information ready:Person's age, weight, and condition Name of the product (ingredients and strength, if known) Time it was swallowed Amount swallowed If the medicine was prescribed for the person Poison Control Your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.Poison control centerFor a POISON EMERGENCY call:1-800-222-1222ANYWHERE IN THE UNITED STATESThis national hotline number will let you talk to experts in poisoning. This ...Read Article Now Book Mark Article This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week. What to Expect at the Emergency Room Take the container to the hospital with you, if possible.The provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms will be treated.Vital signsVital signs reflect essential body functions, including your heartbeat, breathing rate, temperature, and blood pressure. Your health care provider m...Read Article Now Book Mark Article Tests that may be done include:Blood and urine tests Chest x-ray Chest x-rayA chest x-ray is an x-ray of the chest, lungs, heart, large arteries, ribs, and diaphragm.Read Article Now Book Mark Article Electrocardiogram (ECG)ElectrocardiogramAn electrocardiogram (ECG) is a test that records the electrical activity of the heart.Read Article Now Book Mark Article Treatment may include: Fluids through a vein (by IV) Laxative Activated charcoal Medicine to reverse the effect of atropine Medicine to reverse the effect of the diphenoxylate Breathing support, including tube through the mouth and connected to a breathing machine (ventilator)VentilatorA ventilator is a machine that breathes for you or helps you breathe. It is also called a breathing machine or respirator. The ventilator: Is attac...Read Article Now Book Mark Article Some people may need to stay in the hospital to be monitored. Outlook (Prognosis) How well someone does depends on how much medicine was swallowed and how quickly treatment is received. The faster medical help is given, the better the chance for recovery.A hospital stay may be needed for more doses of the medicines that reverse the effects of the drug. Complications, such as pneumonia, muscle damage from lying on a hard surface for a prolonged period of time, or brain damage from lack of oxygen may result in permanent disability. However, unless there are complications, long-term effects and death are rare.People who quickly receive medicine to reverse the effect of the opioid usually get better within 24 to 48 hours. However, children do not do as well.Open ReferencesReferencesAronson JK. Atropine. In: Aronson JK, ed. Meyler's Side Effects of Drugs. 16th ed. Waltham, MA: Elsevier; 2016:754-755.Cole JB. Cardiovascular drugs. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 142.Nikolaides JK, Thompson TM. Opioids. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 151.AllVideoImagesTogRelated Information Review Date: 11/2/2023 Reviewed By: Jesse Borke, MD, CPE, FAAEM, FACEP, Attending Physician at Kaiser Permanente, Orange County, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. No warranty of any kind, either expressed or implied, is made as to the accuracy, reliability, timeliness, or correctness of any translations made by a third-party service of the information provided herein into any other language. © 1997- A.D.A.M., a business unit of Ebix, Inc. Any duplication or distribution of the information contained herein is strictly prohibited. © 1997- All rights reserved. A.D.A.M. content is best viewed in IE9 or above, Firefox and Google Chrome browser.Content is best viewed in IE9 or above, Firefox and Google Chrome browser.
Lomotil overdoseDiphenoxylate with atropine overdose; Atropine with diphenoxylate overdoseLomotil is a prescription medicine used to treat diarrhea. Lomotil overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose.This article is for information only. DO NOT use it to treat or manage an actual overdose. If you or someone you are with has an overdose, call your local emergency number (such as 911), or your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States.OverdoseAn overdose is when you take more than the recommended amount of something, often a medicine or drug. An overdose may result in serious, harmful sym...Read Article Now Book Mark Article Poisonous Ingredient Lomotil contains two medicines that can be harmful in large amounts. They are:Atropine Diphenoxylate (an opioid) Where Found Medicines with these names contain atropine and diphenoxylate:Lofene Logen Lomanate Lomotil LonoxOther medicines may also contain atropine and diphenoxylate. Symptoms Symptoms of a Lomotil overdose include:Slow breathing, or breathing stops Pounding heartbeat (palpitations) Pounding heartbeatPalpitations are feelings or sensations that your heart is pounding or racing. They can be felt in your chest, throat, or neck. You may:Have an unpl...Read Article Now Book Mark Article Rapid heartbeat Rapid heartbeatPalpitations are feelings or sensations that your heart is pounding or racing. They can be felt in your chest, throat, or neck. You may:Have an unpl...Read Article Now Book Mark Article Slowdown or stoppage of the bowels Slowdown or stoppage of the bowelsIntestinal obstruction is a partial or complete blockage of the bowel. The contents of the intestine cannot pass through it.Read Article Now Book Mark Article Coma (decreased level of consciousness, lack of responsiveness) ComaDecreased alertness is a state of reduced awareness and is often a serious condition. A coma is the most severe state of decreased alertness from whi...Read Article Now Book Mark Article Constipation ConstipationConstipation in infants and children means they have hard stools or have problems passing stools. A child may have pain while passing stools or may ...Read Article Now Book Mark Article Seizures (convulsions) SeizuresA seizure is the physical changes in behavior that occurs during an episode of specific types of abnormal electrical activity in the brain. The term ...Read Article Now Book Mark Article Drowsiness DrowsinessDrowsiness refers to feeling more sleepy than normal during the day. People who are drowsy may fall asleep when they do not want to or at times whic...Read Article Now Book Mark Article Dry mucous membranes in the mouth Eye changes in pupil size (may be small, normal-sized, or large) Eyes move quickly from side to side Flushed skin Flushed skinSkin blushing or flushing is a sudden reddening of the face, neck, or upper chest due to increased blood flow.Read Article Now Book Mark Article Hallucinations (seeing or hearing things that aren't there) HallucinationsHallucinations involve sensing things such as visions, sounds, or smells that seem real but are not. These things are created by the mind.Read Article Now Book Mark Article Restlessness Urination difficulty VomitingNote: Symptoms may take up to 12 hours to appear. Home Care Seek medical help right away. Do not make a person throw up unless poison control or a health care provider tells you to. Before Calling Emergency Have this information ready:Person's age, weight, and condition Name of the product (ingredients and strength, if known) Time it was swallowed Amount swallowed If the medicine was prescribed for the person Poison Control Your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.Poison control centerFor a POISON EMERGENCY call:1-800-222-1222ANYWHERE IN THE UNITED STATESThis national hotline number will let you talk to experts in poisoning. This ...Read Article Now Book Mark Article This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week. What to Expect at the Emergency Room Take the container to the hospital with you, if possible.The provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure. Symptoms will be treated.Vital signsVital signs reflect essential body functions, including your heartbeat, breathing rate, temperature, and blood pressure. Your health care provider m...Read Article Now Book Mark Article Tests that may be done include:Blood and urine tests Chest x-ray Chest x-rayA chest x-ray is an x-ray of the chest, lungs, heart, large arteries, ribs, and diaphragm.Read Article Now Book Mark Article Electrocardiogram (ECG)ElectrocardiogramAn electrocardiogram (ECG) is a test that records the electrical activity of the heart.Read Article Now Book Mark Article Treatment may include: Fluids through a vein (by IV) Laxative Activated charcoal Medicine to reverse the effect of atropine Medicine to reverse the effect of the diphenoxylate Breathing support, including tube through the mouth and connected to a breathing machine (ventilator)VentilatorA ventilator is a machine that breathes for you or helps you breathe. It is also called a breathing machine or respirator. The ventilator: Is attac...Read Article Now Book Mark Article Some people may need to stay in the hospital to be monitored. Outlook (Prognosis) How well someone does depends on how much medicine was swallowed and how quickly treatment is received. The faster medical help is given, the better the chance for recovery.A hospital stay may be needed for more doses of the medicines that reverse the effects of the drug. Complications, such as pneumonia, muscle damage from lying on a hard surface for a prolonged period of time, or brain damage from lack of oxygen may result in permanent disability. However, unless there are complications, long-term effects and death are rare.People who quickly receive medicine to reverse the effect of the opioid usually get better within 24 to 48 hours. However, children do not do as well.Open ReferencesReferencesAronson JK. Atropine. In: Aronson JK, ed. Meyler's Side Effects of Drugs. 16th ed. Waltham, MA: Elsevier; 2016:754-755.Cole JB. Cardiovascular drugs. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 142.Nikolaides JK, Thompson TM. Opioids. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 151.