BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuAmitriptyline hydrochloride overdoseElavil overdose; Adepril overdose; Endep overdose; Enovil overdose; Trepiline overdoseAmitriptyline hydrochloride is a type of prescription medicine called a tricyclic antidepressant. It is used to treat depression. Amitriptyline hydrochloride overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose.This article is for information only. DO NOT use it to treat or manage an actual overdose. If you or someone you are with has an overdose, call your local emergency number (such as 911), or your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. OverdoseAn overdose is when you take more than the recommended amount of something, often a medicine or drug. An overdose may result in serious, harmful sym...Read Article Now Book Mark Article Poisonous Ingredient Amitriptyline can be harmful in large amounts. Where Found Amitriptyline hydrochloride is a prescription medicine. It is sold under these brand names:Adepril Emitrip Enovil Trepiline Tryptanol VanatripOther medicines may also contain amitriptyline hydrochloride. Symptoms Below are symptoms of an amitriptyline hydrochloride overdose in different parts of the body. These symptoms may occur more often or be more severe in people who also take certain other medicines that affect serotonin, a chemical in the brain.AIRWAYS AND LUNGSSlowed, labored breathingSlowed, labored breathingBreathing difficulty may involve:Difficult breathing Uncomfortable breathingFeeling like you are not getting enough airRead Article Now Book Mark Article BLADDER AND KIDNEYSCannot urinate Urine does not flow easilyUrine does not flow easilyDifficulty starting or maintaining a urine stream is called urinary hesitancy.Read Article Now Book Mark Article EYES, EARS, NOSE, AND THROATBlurred vision Blurred visionThere are many types of eye problems and vision disturbances, such as: Halos Blurred vision (the loss of sharpness of vision and the inability to see...Read Article Now Book Mark Article Dilated (wide) pupils Eye pain in people at risk for a type of glaucoma GlaucomaGlaucoma is a group of eye conditions that can damage the optic nerve. This nerve sends the images you see to your brain. Most often, optic nerve da...Read Article Now Book Mark Article Dry mouthDry mouthDry mouth occurs when you don't make enough saliva. This causes your mouth to feel dry and uncomfortable. Dry mouth that is ongoing may be a sign o...Read Article Now Book Mark Article HEART AND BLOODIrregular heart rate Low blood pressure Low blood pressureLow blood pressure occurs when blood pressure is much lower than normal. This means the heart, brain, and other parts of the body may not get enough...Read Article Now Book Mark Article Rapid heartbeat Rapid heartbeatWolff-Parkinson-White (WPW) syndrome is a condition in which there is an extra electrical pathway in the heart that leads to periods of rapid heart r...Read Article Now Book Mark Article ShockShockShock is a life-threatening condition that occurs when the body is not getting enough blood flow. Lack of blood flow means the cells and organs do n...Read Article Now Book Mark Article NERVOUS SYSTEMAgitation AgitationAgitation is an unpleasant state of extreme arousal. An agitated person may feel stirred up, excited, tense, confused, or irritable.Read Article Now Book Mark Article Coma ComaDecreased alertness is a state of reduced awareness and is often a serious condition. A coma is the most severe state of decreased alertness from whi...Read Article Now Book Mark Article Seizures SeizuresA seizure is the physical changes in behavior that occurs during an episode of specific types of abnormal electrical activity in the brain. The term ...Read Article Now Book Mark Article Drowsiness Hallucinations HallucinationsHallucinations involve sensing things such as visions, sounds, or smells that seem real but are not. These things are created by the mind.Read Article Now Book Mark Article Headache HeadacheA headache is pain or discomfort in the head, scalp, or neck. Serious causes of headaches are rare. Most people with headaches can feel much better...Read Article Now Book Mark Article Inability to concentrate Lack of alertness (stupor) StuporDecreased alertness is a state of reduced awareness and is often a serious condition. A coma is the most severe state of decreased alertness from whi...Read Article Now Book Mark Article Muscle rigidity or stiffness of the limbs Restlessness RestlessnessAgitation is an unpleasant state of extreme arousal. An agitated person may feel stirred up, excited, tense, confused, or irritable.Read Article Now Book Mark Article Uncoordinated movementUncoordinated movementUncoordinated movement is due to a muscle control problem that causes an inability to coordinate movements. It leads to a jerky, unsteady, to-and-fr...Read Article Now Book Mark Article STOMACH AND INTESTINESConstipation VomitingVomitingNausea is feeling an urge to vomit. It is often called "being sick to your stomach. "Vomiting or throwing-up forces the contents of the stomach up t...Read Article Now Book Mark Article Home Care This can be a very serious overdose. Seek medical help right away. Do not make the person throw up unless poison control or a health care provider tells you to. Before Calling Emergency Have this information ready: Person's age, weight, and condition Name of the product (ingredients and strength, if known) Time it was swallowed Amount swallowed If the medicine was prescribed for the person Poison Control Your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.Poison control centerFor a POISON EMERGENCY call:1-800-222-1222ANYWHERE IN THE UNITED STATESThis national hotline number will let you talk to experts in poisoning. This ...Read Article Now Book Mark Article This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week. What to Expect at the Emergency Room Take the container to the hospital with you, if possible. The provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure.Tests that may be done include:Blood and urine tests CT scan CT scanA computed tomography (CT) scan is an imaging method that uses x-rays to create pictures of cross-sections of the body. Related tests include:Abdomin...Read Article Now Book Mark Article Chest x-ray Chest x-rayA chest x-ray is an x-ray of the chest, lungs, heart, large arteries, ribs, and diaphragm.Read Article Now Book Mark Article Electrocardiogram (ECG)ElectrocardiogramAn electrocardiogram (ECG) is a test that records the electrical activity of the heart.Read Article Now Book Mark Article Treatment may include:Fluids through a vein (by IV) Medicine called an antidote to reverse the effects of the poison and treat symptoms, such as sodium bicarbonate or lidocaine Activated charcoal Laxatives Breathing support, including a tube through the mouth into the lungs and connected to a breathing machine (ventilator)Breathing machineA ventilator is a machine that breathes for you or helps you breathe. It is also called a breathing machine or respirator. The ventilator: Is attac...Read Article Now Book Mark Article Outlook (Prognosis) An amitriptyline hydrochloride overdose can be very serious.People who swallow too much of this medicine are almost always admitted to the hospital.How well someone does depends on how much of the medicine was swallowed and how quickly treatment is given. The faster a person gets medical help, the better the chance of recovery. Complications such as heart rhythm disturbances, pneumonia, muscle damage from lying on a hard surface for a long period of time, or brain damage from lack of oxygen may result in permanent disability. Death can occur.Open ReferencesReferencesAronson JK. Tricyclic antidepressants. In: Aronson JK, ed. Meyler's Side Effects of Drugs. 16th ed. Waltham, MA: Elsevier; 2016:146-169.Levine MD, Ruha AM. Antidepressants. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 141.AllVideoImagesTogRelated Information Review Date: 11/2/2023 Reviewed By: Jesse Borke, MD, CPE, FAAEM, FACEP, Attending Physician at Kaiser Permanente, Orange County, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. No warranty of any kind, either expressed or implied, is made as to the accuracy, reliability, timeliness, or correctness of any translations made by a third-party service of the information provided herein into any other language. © 1997- A.D.A.M., a business unit of Ebix, Inc. Any duplication or distribution of the information contained herein is strictly prohibited. © 1997- All rights reserved. A.D.A.M. content is best viewed in IE9 or above, Firefox and Google Chrome browser.Content is best viewed in IE9 or above, Firefox and Google Chrome browser.
Amitriptyline hydrochloride overdoseElavil overdose; Adepril overdose; Endep overdose; Enovil overdose; Trepiline overdoseAmitriptyline hydrochloride is a type of prescription medicine called a tricyclic antidepressant. It is used to treat depression. Amitriptyline hydrochloride overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose.This article is for information only. DO NOT use it to treat or manage an actual overdose. If you or someone you are with has an overdose, call your local emergency number (such as 911), or your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. OverdoseAn overdose is when you take more than the recommended amount of something, often a medicine or drug. An overdose may result in serious, harmful sym...Read Article Now Book Mark Article Poisonous Ingredient Amitriptyline can be harmful in large amounts. Where Found Amitriptyline hydrochloride is a prescription medicine. It is sold under these brand names:Adepril Emitrip Enovil Trepiline Tryptanol VanatripOther medicines may also contain amitriptyline hydrochloride. Symptoms Below are symptoms of an amitriptyline hydrochloride overdose in different parts of the body. These symptoms may occur more often or be more severe in people who also take certain other medicines that affect serotonin, a chemical in the brain.AIRWAYS AND LUNGSSlowed, labored breathingSlowed, labored breathingBreathing difficulty may involve:Difficult breathing Uncomfortable breathingFeeling like you are not getting enough airRead Article Now Book Mark Article BLADDER AND KIDNEYSCannot urinate Urine does not flow easilyUrine does not flow easilyDifficulty starting or maintaining a urine stream is called urinary hesitancy.Read Article Now Book Mark Article EYES, EARS, NOSE, AND THROATBlurred vision Blurred visionThere are many types of eye problems and vision disturbances, such as: Halos Blurred vision (the loss of sharpness of vision and the inability to see...Read Article Now Book Mark Article Dilated (wide) pupils Eye pain in people at risk for a type of glaucoma GlaucomaGlaucoma is a group of eye conditions that can damage the optic nerve. This nerve sends the images you see to your brain. Most often, optic nerve da...Read Article Now Book Mark Article Dry mouthDry mouthDry mouth occurs when you don't make enough saliva. This causes your mouth to feel dry and uncomfortable. Dry mouth that is ongoing may be a sign o...Read Article Now Book Mark Article HEART AND BLOODIrregular heart rate Low blood pressure Low blood pressureLow blood pressure occurs when blood pressure is much lower than normal. This means the heart, brain, and other parts of the body may not get enough...Read Article Now Book Mark Article Rapid heartbeat Rapid heartbeatWolff-Parkinson-White (WPW) syndrome is a condition in which there is an extra electrical pathway in the heart that leads to periods of rapid heart r...Read Article Now Book Mark Article ShockShockShock is a life-threatening condition that occurs when the body is not getting enough blood flow. Lack of blood flow means the cells and organs do n...Read Article Now Book Mark Article NERVOUS SYSTEMAgitation AgitationAgitation is an unpleasant state of extreme arousal. An agitated person may feel stirred up, excited, tense, confused, or irritable.Read Article Now Book Mark Article Coma ComaDecreased alertness is a state of reduced awareness and is often a serious condition. A coma is the most severe state of decreased alertness from whi...Read Article Now Book Mark Article Seizures SeizuresA seizure is the physical changes in behavior that occurs during an episode of specific types of abnormal electrical activity in the brain. The term ...Read Article Now Book Mark Article Drowsiness Hallucinations HallucinationsHallucinations involve sensing things such as visions, sounds, or smells that seem real but are not. These things are created by the mind.Read Article Now Book Mark Article Headache HeadacheA headache is pain or discomfort in the head, scalp, or neck. Serious causes of headaches are rare. Most people with headaches can feel much better...Read Article Now Book Mark Article Inability to concentrate Lack of alertness (stupor) StuporDecreased alertness is a state of reduced awareness and is often a serious condition. A coma is the most severe state of decreased alertness from whi...Read Article Now Book Mark Article Muscle rigidity or stiffness of the limbs Restlessness RestlessnessAgitation is an unpleasant state of extreme arousal. An agitated person may feel stirred up, excited, tense, confused, or irritable.Read Article Now Book Mark Article Uncoordinated movementUncoordinated movementUncoordinated movement is due to a muscle control problem that causes an inability to coordinate movements. It leads to a jerky, unsteady, to-and-fr...Read Article Now Book Mark Article STOMACH AND INTESTINESConstipation VomitingVomitingNausea is feeling an urge to vomit. It is often called "being sick to your stomach. "Vomiting or throwing-up forces the contents of the stomach up t...Read Article Now Book Mark Article Home Care This can be a very serious overdose. Seek medical help right away. Do not make the person throw up unless poison control or a health care provider tells you to. Before Calling Emergency Have this information ready: Person's age, weight, and condition Name of the product (ingredients and strength, if known) Time it was swallowed Amount swallowed If the medicine was prescribed for the person Poison Control Your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.Poison control centerFor a POISON EMERGENCY call:1-800-222-1222ANYWHERE IN THE UNITED STATESThis national hotline number will let you talk to experts in poisoning. This ...Read Article Now Book Mark Article This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week. What to Expect at the Emergency Room Take the container to the hospital with you, if possible. The provider will measure and monitor the person's vital signs, including temperature, pulse, breathing rate, and blood pressure.Tests that may be done include:Blood and urine tests CT scan CT scanA computed tomography (CT) scan is an imaging method that uses x-rays to create pictures of cross-sections of the body. Related tests include:Abdomin...Read Article Now Book Mark Article Chest x-ray Chest x-rayA chest x-ray is an x-ray of the chest, lungs, heart, large arteries, ribs, and diaphragm.Read Article Now Book Mark Article Electrocardiogram (ECG)ElectrocardiogramAn electrocardiogram (ECG) is a test that records the electrical activity of the heart.Read Article Now Book Mark Article Treatment may include:Fluids through a vein (by IV) Medicine called an antidote to reverse the effects of the poison and treat symptoms, such as sodium bicarbonate or lidocaine Activated charcoal Laxatives Breathing support, including a tube through the mouth into the lungs and connected to a breathing machine (ventilator)Breathing machineA ventilator is a machine that breathes for you or helps you breathe. It is also called a breathing machine or respirator. The ventilator: Is attac...Read Article Now Book Mark Article Outlook (Prognosis) An amitriptyline hydrochloride overdose can be very serious.People who swallow too much of this medicine are almost always admitted to the hospital.How well someone does depends on how much of the medicine was swallowed and how quickly treatment is given. The faster a person gets medical help, the better the chance of recovery. Complications such as heart rhythm disturbances, pneumonia, muscle damage from lying on a hard surface for a long period of time, or brain damage from lack of oxygen may result in permanent disability. Death can occur.Open ReferencesReferencesAronson JK. Tricyclic antidepressants. In: Aronson JK, ed. Meyler's Side Effects of Drugs. 16th ed. Waltham, MA: Elsevier; 2016:146-169.Levine MD, Ruha AM. Antidepressants. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 141.