BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuCyproheptadine overdoseCyproheptadine is a type of medicine called an antihistamine. These medicines are used to relieve allergy symptoms. Cyproheptadine overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose.This article is for information only. DO NOT use it to treat or manage an actual overdose. If you or someone you are with overdoses, call your local emergency number (such as 911), or your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. Poisonous Ingredient Cyproheptadine can be harmful in large amounts. Where Found Cyproheptadine is an allergy medicine. Symptoms Below are symptoms of a cyproheptadine overdose in different parts of the body.BLADDER AND KIDNEYSInability to urinate Difficulty urinating EYES, EARS, NOSE, MOUTH, AND THROATBlurred vision Blurred visionThere are many types of eye problems and vision disturbances, such as: Halos Blurred vision (the loss of sharpness of vision and the inability to see...Read Article Now Book Mark Article Dilated (wide) pupils Dry mouth Ringing in the ears (tinnitus) TinnitusTinnitus is the medical term for "hearing" noises in your ears. It occurs when there is no outside source of the sounds. Tinnitus is often called "r...Read Article Now Book Mark Article HEART AND BLOOD VESSELSRapid heartbeat Rapid heartbeatPalpitations are feelings or sensations that your heart is pounding or racing. They can be felt in your chest, throat, or neck. You may:Have an unpl...Read Article Now Book Mark Article Increased blood pressure NERVOUS SYSTEMAgitation AgitationAgitation is an unpleasant state of extreme arousal. An agitated person may feel stirred up, excited, tense, confused, or irritable.Read Article Now Book Mark Article Coma (lack of responsiveness) ComaDecreased alertness is a state of reduced awareness and is often a serious condition. A coma is the most severe state of decreased alertness from whi...Read Article Now Book Mark Article Convulsions (seizures) ConvulsionsA seizure is the physical changes in behavior that occurs during an episode of specific types of abnormal electrical activity in the brain. The term ...Read Article Now Book Mark Article Delirium (acute confusion) DeliriumDelirium is sudden severe confusion due to rapid changes in brain function that can occur with physical or mental illness.Read Article Now Book Mark Article Disorientation, hallucinations HallucinationsHallucinations involve sensing things such as visions, sounds, or smells that seem real but are not. These things are created by the mind.Read Article Now Book Mark Article Drowsiness DrowsinessDrowsiness refers to feeling more sleepy than normal during the day. People who are drowsy may fall asleep when they do not want to or at times whic...Read Article Now Book Mark Article Fever Irregular or rapid heartbeat Nervousness Tremor (shaking) TremorA tremor is a type of shaking movement. A tremor is most often noticed in the hands and arms. It may affect any body part, including the head, tong...Read Article Now Book Mark Article Unsteadiness, weakness UnsteadinessWalking abnormalities can be caused by many different types of problems. Problems with the joints, (such as arthritis), bones (such as deformities),...Read Article Now Book Mark Article SKINFlushed and dry skin STOMACH AND INTESTINESConstipation Nausea and vomiting Before Calling Emergency Have this information ready: The person's age, weight, and condition Name of product (ingredients and strength, if known) Time it was swallowed Amount swallowed If the medicine was prescribed for the person Poison Control Your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.Poison control centerFor a POISON EMERGENCY call:1-800-222-1222ANYWHERE IN THE UNITED STATESThis national hotline number will let you talk to experts in poisoning. This ...Read Article Now Book Mark Article This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week. What to Expect at the Emergency Room Take the container to the hospital with you, if possible.Your health care provider will measure and monitor your vital signs, including temperature, pulse, breathing rate, and blood pressure.Tests that may be done include:Blood and urine tests Chest x-ray CT scan (advanced imaging) of the brain for neurologic symptoms Electrocardiogram (ECG)ElectrocardiogramAn electrocardiogram (ECG) is a test that records the electrical activity of the heart.Read Article Now Book Mark Article Treatment may include:Activated charcoal Fluids through a vein (by IV) Medicine to treat symptoms Laxative Breathing support, including oxygen, tube through the mouth into the lungs, and breathing machine (ventilator) Outlook (Prognosis) If the person survives the first 24 hours, survival is likely. Few people actually die from an antihistamine overdose. Very high doses of antihistamines can cause serious heart rhythm disturbances, which may result in death.Open ReferencesReferencesAronson JK. Anticholinergic drugs. In: Aronson JK, ed. Meyler's Side Effects of Drugs. 16th ed. Waltham, MA: Elsevier; 2016:534-539.Hoppe JA, Monte AA. Anticholinergics. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 140.AllVideoImagesTogRelated Information Review Date: 7/1/2023 Reviewed By: Jesse Borke, MD, CPE, FAAEM, FACEP, Attending Physician at Kaiser Permanente, Orange County, CA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. 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Cyproheptadine overdoseCyproheptadine is a type of medicine called an antihistamine. These medicines are used to relieve allergy symptoms. Cyproheptadine overdose occurs when someone takes more than the normal or recommended amount of this medicine. This can be by accident or on purpose.This article is for information only. DO NOT use it to treat or manage an actual overdose. If you or someone you are with overdoses, call your local emergency number (such as 911), or your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. Poisonous Ingredient Cyproheptadine can be harmful in large amounts. Where Found Cyproheptadine is an allergy medicine. Symptoms Below are symptoms of a cyproheptadine overdose in different parts of the body.BLADDER AND KIDNEYSInability to urinate Difficulty urinating EYES, EARS, NOSE, MOUTH, AND THROATBlurred vision Blurred visionThere are many types of eye problems and vision disturbances, such as: Halos Blurred vision (the loss of sharpness of vision and the inability to see...Read Article Now Book Mark Article Dilated (wide) pupils Dry mouth Ringing in the ears (tinnitus) TinnitusTinnitus is the medical term for "hearing" noises in your ears. It occurs when there is no outside source of the sounds. Tinnitus is often called "r...Read Article Now Book Mark Article HEART AND BLOOD VESSELSRapid heartbeat Rapid heartbeatPalpitations are feelings or sensations that your heart is pounding or racing. They can be felt in your chest, throat, or neck. You may:Have an unpl...Read Article Now Book Mark Article Increased blood pressure NERVOUS SYSTEMAgitation AgitationAgitation is an unpleasant state of extreme arousal. An agitated person may feel stirred up, excited, tense, confused, or irritable.Read Article Now Book Mark Article Coma (lack of responsiveness) ComaDecreased alertness is a state of reduced awareness and is often a serious condition. A coma is the most severe state of decreased alertness from whi...Read Article Now Book Mark Article Convulsions (seizures) ConvulsionsA seizure is the physical changes in behavior that occurs during an episode of specific types of abnormal electrical activity in the brain. The term ...Read Article Now Book Mark Article Delirium (acute confusion) DeliriumDelirium is sudden severe confusion due to rapid changes in brain function that can occur with physical or mental illness.Read Article Now Book Mark Article Disorientation, hallucinations HallucinationsHallucinations involve sensing things such as visions, sounds, or smells that seem real but are not. These things are created by the mind.Read Article Now Book Mark Article Drowsiness DrowsinessDrowsiness refers to feeling more sleepy than normal during the day. People who are drowsy may fall asleep when they do not want to or at times whic...Read Article Now Book Mark Article Fever Irregular or rapid heartbeat Nervousness Tremor (shaking) TremorA tremor is a type of shaking movement. A tremor is most often noticed in the hands and arms. It may affect any body part, including the head, tong...Read Article Now Book Mark Article Unsteadiness, weakness UnsteadinessWalking abnormalities can be caused by many different types of problems. Problems with the joints, (such as arthritis), bones (such as deformities),...Read Article Now Book Mark Article SKINFlushed and dry skin STOMACH AND INTESTINESConstipation Nausea and vomiting Before Calling Emergency Have this information ready: The person's age, weight, and condition Name of product (ingredients and strength, if known) Time it was swallowed Amount swallowed If the medicine was prescribed for the person Poison Control Your local poison control center can be reached directly by calling the national toll-free Poison Help hotline (1-800-222-1222) from anywhere in the United States. This national hotline will let you talk to experts in poisoning. They will give you further instructions.Poison control centerFor a POISON EMERGENCY call:1-800-222-1222ANYWHERE IN THE UNITED STATESThis national hotline number will let you talk to experts in poisoning. This ...Read Article Now Book Mark Article This is a free and confidential service. All local poison control centers in the United States use this national number. You should call if you have any questions about poisoning or poison prevention. It does NOT need to be an emergency. You can call for any reason, 24 hours a day, 7 days a week. What to Expect at the Emergency Room Take the container to the hospital with you, if possible.Your health care provider will measure and monitor your vital signs, including temperature, pulse, breathing rate, and blood pressure.Tests that may be done include:Blood and urine tests Chest x-ray CT scan (advanced imaging) of the brain for neurologic symptoms Electrocardiogram (ECG)ElectrocardiogramAn electrocardiogram (ECG) is a test that records the electrical activity of the heart.Read Article Now Book Mark Article Treatment may include:Activated charcoal Fluids through a vein (by IV) Medicine to treat symptoms Laxative Breathing support, including oxygen, tube through the mouth into the lungs, and breathing machine (ventilator) Outlook (Prognosis) If the person survives the first 24 hours, survival is likely. Few people actually die from an antihistamine overdose. Very high doses of antihistamines can cause serious heart rhythm disturbances, which may result in death.Open ReferencesReferencesAronson JK. Anticholinergic drugs. In: Aronson JK, ed. Meyler's Side Effects of Drugs. 16th ed. Waltham, MA: Elsevier; 2016:534-539.Hoppe JA, Monte AA. Anticholinergics. In: Walls RM, ed. Rosen's Emergency Medicine: Concepts and Clinical Practice. 10th ed. Philadelphia, PA: Elsevier; 2023:chap 140.