Infant of diabetic mother

Definition

A fetus (baby) of a mother with diabetes may be exposed to high blood sugar (glucose) levels throughout the pregnancy.

Alternative Names

IDM; Gestational diabetes - IDM; Neonatal care - diabetic mother

Causes

There are two forms of diabetes during pregnancy:

If diabetes is not well controlled during pregnancy, the baby is exposed to high blood sugar levels. This can affect the baby and mother during pregnancy, at the time of birth, and after birth.

Infants of diabetic mothers (IDM) are often larger than other babies, especially if diabetes is not well-controlled. This may make vaginal birth harder and may increase the risk for nerve injuries and other trauma during birth. Also, cesarean births are more likely.

An IDM is more likely to have periods of low blood sugar (hypoglycemia) shortly after birth, and during the first few days of life. This is because the baby has been used to getting more sugar than needed from the mother. They have a higher insulin level than needed after birth. Insulin lowers the blood sugar. It can take days for babies' insulin levels to adjust after birth.

IDMs are more likely to have:

If diabetes is not well-controlled, chances of miscarriage or stillbirth are higher.

An IDM has a higher risk of birth defects if the mother has pre-existing diabetes that is not well controlled from the very beginning.

Symptoms

The infant is often larger than usual for babies born after the same length of time in the mother's womb (large for gestational age). In some cases, especially if mothers have more longstanding illness, the baby may be smaller (small for gestational age).

Other symptoms may include:

Exams and Tests

Before the baby is born:

After the baby is born:

Treatment

All infants who are born to mothers with diabetes should be tested for low blood sugar, even if they have no symptoms.

Efforts are made to ensure the baby has enough glucose in the blood:

Rarely, the infant may need breathing support or medicines to treat other effects of diabetes. High bilirubin levels are treated with light therapy (phototherapy).

Outlook (Prognosis)

In most cases, an infant's symptoms go away within hours, days, or a few weeks. However, an enlarged heart may take several months to get better.

Very rarely, blood sugar may be so low as to cause brain damage.

Possible Complications

The risk of stillbirth is higher in women with diabetes that is not well controlled. There is also an increased risk for a number of birth defects or problems:

When to Contact a Medical Professional

If you are pregnant and getting regular prenatal care, routine testing will show if you develop gestational diabetes.

If you are pregnant or planning pregnancy and have diabetes that is not under control, contact your health care provider right away.

If you are pregnant and are not receiving prenatal care, contact a provider for an appointment.

Prevention

Women with diabetes need special care during pregnancy to prevent problems. Controlling blood sugar can prevent many problems.

Carefully monitoring the infant in the first hours and days after birth may prevent health problems due to low blood sugar.

References

Garg M, Devaskar SU. Disorders of carbohydrate metabolism in the neonate. In: Martin RJ, Fanaroff AA, eds. Fanaroff and Martin's Neonatal-Perinatal Medicine: Diseases of the Fetus and Infant. 12th ed. Philadelphia, PA: Elsevier; 2025:chap 90.

Landon MB, Catalano PM, Gabbe SG. Diabetes mellitus complicating pregnancy. In: Landon MB, Galan HL, Jauniaux ERM, et al, eds. Gabbe's Obstetrics: Normal and Problem Pregnancies. 8th ed. Philadelphia, PA: Elsevier; 2021:chap 45.

Moore TR, Hauguel-De Mouzon S, Catalano P. Diabetes in pregnancy. In: Resnik R, Lockwood CJ, Moore TR, Greene MF, Copel JA, Silver RM, eds. Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice. 8th ed. Philadelphia, PA: Elsevier; 2019:chap 59.

Paauw ND, Stegeman R, de Vroede MAMJ, Termote JUM, Freund MW, Breur JMPJ. Neonatal cardiac hypertrophy: the role of hyperinsulinism-a review of literature. Eur J Pediatr. 2020;179(1):39-50. PMID: 31840185 pubmed.ncbi.nlm.nih.gov/31840185/.

Sheanon NM, Muglia LJ. The endocrine system. In: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Textbook of Pediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020:chap 127.


Review Date: 12/31/2023
Reviewed By: Mary J. Terrell, MD, IBCLC, Neonatologist, Cape Fear Valley Medical Center, Fayetteville, NC. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
adam.com