BACK TOTOP Browse A-ZSearchBrowse A-ZABCDEFGHIJKLMNOPQRSTUVWXYZ0-9 E-mail FormEmail ResultsName:Email address:Recipients Name:Recipients address:Message: Print-FriendlyBookmarksbookmarks-menuAgranulocytosisGranulocytopenia; GranulopeniaWhite blood cells fight infections from bacteria, viruses, fungi, and other germs. One important type of white blood cell is the granulocyte, which is made in the bone marrow and travels in the blood throughout the body. Granulocytes sense infections, gather at sites of infection, and destroy the germs.When the body has too few granulocytes, the condition is called agranulocytosis. This makes it harder for the body to fight off germs. As a result, the person is more likely to get sick from infections. Causes Agranulocytosis may be caused by:Autoimmune disorders Autoimmune disordersAn autoimmune disorder occurs when the body's immune system attacks and destroys healthy body tissue by mistake. There are more than 80 autoimmune d...ImageRead Article Now Book Mark Article Bone marrow diseases, such as myelodysplasia or large granular lymphocyte (LGL) leukemia Certain medicines used to treat diseases, including cancer Certain street drugs Poor nutrition Preparation for bone marrow transplant Bone marrow transplantA bone marrow transplant is a procedure to replace damaged or diseased bone marrow with healthy bone marrow stem cells. Bone marrow is the soft, fatt...ImageRead Article Now Book Mark Article Problem with genes Symptoms Symptoms of this condition may include:Fever Chills Malaise General weakness Sore throat Mouth and throat ulcers Bone pain Bone painBone pain or tenderness is aching or other discomfort in one or more bones.ImageRead Article Now Book Mark Article Pneumonia PneumoniaPneumonia is a breathing (respiratory) condition in which there is an infection of the lung. This article covers community-acquired pneumonia (CAP). ...ImageRead Article Now Book Mark Article ShockShockSeptic shock is a serious condition that occurs when a body-wide infection leads to dangerously low blood pressure.Read Article Now Book Mark Article Exams and Tests A white blood cell differential test will be done to measure the percentage of each type of white blood cell in your blood.White blood cell differentialThe blood differential test measures the percentage of each type of white blood cell (WBC) that you have in your blood. It also reveals if there are...ImageRead Article Now Book Mark Article Other tests to diagnose the condition may include:Bone marrow biopsy Bone marrow biopsyA bone marrow biopsy is the removal of marrow from inside bone. Bone marrow is the soft tissue inside bones that helps form blood cells. It is foun...ImageRead Article Now Book Mark Article Biopsy of mouth ulcer Biopsy of mouth ulcerAn oropharynx lesion biopsy is surgery in which tissue from an abnormal growth or mouth sore is removed and checked for disease.ImageRead Article Now Book Mark Article Neutrophil antibody studies (blood test) Treatment Treatment depends on the cause of the low white blood cell count. For example, if a medicine is the cause, stopping or changing to another medicine may help. In other cases, medicines to help the body make more white blood cells will be used. Outlook (Prognosis) Treating or removing the cause often results in a good outcome. Prevention If you are having treatment or taking medicine that could cause agranulocytosis, your health care provider will use blood tests to monitor you.Open ReferencesReferencesCook JR. Bone marrow failure syndromes. In: Hsi ED, ed. Hematopathology. 3rd ed. Philadelphia, PA: Elsevier; 2018:chap 5.Klokkevold PR, Mealey BL. Influence of systemic conditions. In: Newman MG, Takei HH, Klokkevold PR, Carranza FA, eds. Newman and Carranza's Clinical Periodontology. 13th ed. Philadelphia, PA: Elsevier; 2019:chap 14.Sive J, Foggo V. Haematological disease. In: Feather A, Randall D, Waterhouse M, eds. Kumar and Clarke's Clinical Medicine. 10th ed. Philadelphia, PA: Elsevier; 2021:chap 17. AllVideoImagesTogBlood cells - illustration Blood is comprised of red blood cells, platelets, and various white blood cells.Blood cellsillustrationBlood cells - illustration Blood is comprised of red blood cells, platelets, and various white blood cells.Blood cellsillustrationRelated Information Granulocyte(Medical Test)Blood differential test(Medical Test) Review Date: 4/29/2022 Reviewed By: Todd Gersten, MD, Hematology/Oncology, Florida Cancer Specialists & Research Institute, Wellington, FL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. 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AgranulocytosisGranulocytopenia; GranulopeniaWhite blood cells fight infections from bacteria, viruses, fungi, and other germs. One important type of white blood cell is the granulocyte, which is made in the bone marrow and travels in the blood throughout the body. Granulocytes sense infections, gather at sites of infection, and destroy the germs.When the body has too few granulocytes, the condition is called agranulocytosis. This makes it harder for the body to fight off germs. As a result, the person is more likely to get sick from infections. Causes Agranulocytosis may be caused by:Autoimmune disorders Autoimmune disordersAn autoimmune disorder occurs when the body's immune system attacks and destroys healthy body tissue by mistake. There are more than 80 autoimmune d...ImageRead Article Now Book Mark Article Bone marrow diseases, such as myelodysplasia or large granular lymphocyte (LGL) leukemia Certain medicines used to treat diseases, including cancer Certain street drugs Poor nutrition Preparation for bone marrow transplant Bone marrow transplantA bone marrow transplant is a procedure to replace damaged or diseased bone marrow with healthy bone marrow stem cells. Bone marrow is the soft, fatt...ImageRead Article Now Book Mark Article Problem with genes Symptoms Symptoms of this condition may include:Fever Chills Malaise General weakness Sore throat Mouth and throat ulcers Bone pain Bone painBone pain or tenderness is aching or other discomfort in one or more bones.ImageRead Article Now Book Mark Article Pneumonia PneumoniaPneumonia is a breathing (respiratory) condition in which there is an infection of the lung. This article covers community-acquired pneumonia (CAP). ...ImageRead Article Now Book Mark Article ShockShockSeptic shock is a serious condition that occurs when a body-wide infection leads to dangerously low blood pressure.Read Article Now Book Mark Article Exams and Tests A white blood cell differential test will be done to measure the percentage of each type of white blood cell in your blood.White blood cell differentialThe blood differential test measures the percentage of each type of white blood cell (WBC) that you have in your blood. It also reveals if there are...ImageRead Article Now Book Mark Article Other tests to diagnose the condition may include:Bone marrow biopsy Bone marrow biopsyA bone marrow biopsy is the removal of marrow from inside bone. Bone marrow is the soft tissue inside bones that helps form blood cells. It is foun...ImageRead Article Now Book Mark Article Biopsy of mouth ulcer Biopsy of mouth ulcerAn oropharynx lesion biopsy is surgery in which tissue from an abnormal growth or mouth sore is removed and checked for disease.ImageRead Article Now Book Mark Article Neutrophil antibody studies (blood test) Treatment Treatment depends on the cause of the low white blood cell count. For example, if a medicine is the cause, stopping or changing to another medicine may help. In other cases, medicines to help the body make more white blood cells will be used. Outlook (Prognosis) Treating or removing the cause often results in a good outcome. Prevention If you are having treatment or taking medicine that could cause agranulocytosis, your health care provider will use blood tests to monitor you.Open ReferencesReferencesCook JR. Bone marrow failure syndromes. In: Hsi ED, ed. Hematopathology. 3rd ed. Philadelphia, PA: Elsevier; 2018:chap 5.Klokkevold PR, Mealey BL. Influence of systemic conditions. In: Newman MG, Takei HH, Klokkevold PR, Carranza FA, eds. Newman and Carranza's Clinical Periodontology. 13th ed. Philadelphia, PA: Elsevier; 2019:chap 14.Sive J, Foggo V. Haematological disease. In: Feather A, Randall D, Waterhouse M, eds. Kumar and Clarke's Clinical Medicine. 10th ed. Philadelphia, PA: Elsevier; 2021:chap 17.