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Cor pulmonale

Show Alternative Names
Right-sided heart failure
Pulmonary heart disease

Cor pulmonale is a condition that causes the right side of the heart to fail. Long-term high blood pressure in the pulmonary arteries of the lung and right ventricle of the heart can lead to cor pulmonale.

Causes

High blood pressure in the pulmonary arteries of the lungs is called pulmonary hypertension. It is the most common cause of cor pulmonale.

In people who have pulmonary hypertension, changes in the small blood vessels inside the lungs can lead to increased blood pressure in the right side of the heart. This makes it harder for the heart to pump blood to the lungs. If this high pressure continues, it puts a strain on the right side of the heart. That strain can cause cor pulmonale.

Lung conditions that cause a low blood oxygen level in the blood over a long time can also lead to cor pulmonale. Some of these are:

Symptoms

Shortness of breath or lightheadedness during activity is often the first symptom of cor pulmonale. You may also have a fast heartbeat and feel like your heart is pounding.

Over time, symptoms occur with lighter activity or even while you are at rest. Symptoms you may have are:

  • Fainting spells during activity
  • Chest discomfort, usually in the front of the chest
  • Chest pain
  • Swelling of the feet or ankles
  • Symptoms of lung disorders, such as wheezing or coughing or phlegm production
  • Bluish lips and fingers (cyanosis)

Exams and Tests

Your health care provider will perform a physical exam and ask about your symptoms. The exam may find:

  • Fluid buildup in your belly
  • Abnormal heart sounds
  • Bluish skin
  • Liver swelling
  • Swelling of the neck veins, which is a sign of high pressure in the right side of the heart
  • Ankle swelling

These tests may help diagnose cor pulmonale as well as its cause:

Treatment

The goal of treatment is to control symptoms. It is important to treat medical problems that cause pulmonary hypertension, because they can lead to cor pulmonale.

Many treatment options are available. In general, the cause of your cor pulmonale will determine which treatment you receive.

If your provider prescribes medicines, you may take them by mouth (oral), receive them through a vein (intravenous or IV), or breathe them in (inhaled). You will be closely monitored during treatment to watch for side effects and to see how well the medicine works for you. Never stop taking your medicines without first talking to your provider.

Other treatments may include:

Important tips to follow:

  • Avoid strenuous activities and heavy lifting.
  • Avoid traveling to high altitudes.
  • Get a yearly flu vaccine, as well as other vaccines, such as the pneumococcal (pneumonia) vaccine, and the COVID-19 vaccine.
  • If you smoke, stop.
  • Limit how much salt you eat. Your provider also may ask you to limit how much fluid you drink during the day.
  • Use oxygen if your provider prescribes it.
  • Women should not get pregnant.

Outlook (Prognosis)

How well you do depends on the cause of your cor pulmonale.

As your illness gets worse, you will need to make changes to your home so that you can manage as well as possible. You will also need help around your house.

Possible Complications

Cor pulmonale may lead to:

  • Life-threatening shortness of breath
  • Severe fluid buildup in your body
  • Shock
  • Death

When to Contact a Medical Professional

Contact your provider if you have shortness of breath or chest pain.

Prevention

Do not smoke. Smoking causes lung disease, which can lead to cor pulmonale.

Review Date: 5/3/2024

Reviewed By

Allen J. Blaivas, DO, Division of Pulmonary, Critical Care, and Sleep Medicine, VA New Jersey Health Care System, Clinical Assistant Professor, Rutgers New Jersey Medical School, East Orange, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

References

Lammi MR, Mathai SC. Pulmonary hypertension: general approach. In: Broaddus VC, Ernst JD, King TE, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 7th ed. Philadelphia, PA: Elsevier; 2022:chap 83.

Maron B. Pulmonary hypertension. In: Libby P, Bonow RO, Mann DL, Tomaselli GF, Braunwald E, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12th ed. Philadelphia, PA: Elsevier; 2022:chap 88.

Disclaimer

The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. No warranty of any kind, either expressed or implied, is made as to the accuracy, reliability, timeliness, or correctness of any translations made by a third-party service of the information provided herein into any other language. © 1997- A.D.A.M., a business unit of Ebix, Inc. Any duplication or distribution of the information contained herein is strictly prohibited.

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Sarcoid, stage IV - chest x-ray

This film shows advanced sarcoid, scarring of the lungs (the light streaking), and cavity formation (the dark areas in the upper right side of the picture).

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Acute vs. chronic conditions

Acute conditions are severe and sudden in onset. This could describe anything from a broken bone to an asthma attack. A chronic condition, by contrast is a long-developing syndrome, such as osteoporosis or asthma. Note that osteoporosis, a chronic condition, may cause a broken bone, an acute condition. An acute asthma attack occurs in the midst of the chronic disease of asthma. Acute conditions, such as a first asthma attack, may lead to a chronic syndrome if untreated.

Illustration

Cor pulmonale - Illustration Thumbnail

Cor pulmonale

Chronically low blood levels of oxygen may lead to pulmonary hypertension (high blood pressure in the lungs), and possibly to cor pulmonale. Cor pulmonale is also called right-sided heart failure, and is characterized by enlargement of the right ventricle. Treatment targets the underlying illness and may include supplemental oxygen, a low-salt diet or calcium channel blockers.

Illustration

Respiratory system - Illustration Thumbnail

Respiratory system

Air is breathed in through the nasal passageways, travels through the trachea and bronchi to the lungs.

Illustration

 
 
Sarcoid, stage IV - chest x-ray - Illustration Thumbnail

Sarcoid, stage IV - chest x-ray

This film shows advanced sarcoid, scarring of the lungs (the light streaking), and cavity formation (the dark areas in the upper right side of the picture).

Illustration

Acute vs. chronic conditions - Illustration Thumbnail

Acute vs. chronic conditions

Acute conditions are severe and sudden in onset. This could describe anything from a broken bone to an asthma attack. A chronic condition, by contrast is a long-developing syndrome, such as osteoporosis or asthma. Note that osteoporosis, a chronic condition, may cause a broken bone, an acute condition. An acute asthma attack occurs in the midst of the chronic disease of asthma. Acute conditions, such as a first asthma attack, may lead to a chronic syndrome if untreated.

Illustration

Cor pulmonale - Illustration Thumbnail

Cor pulmonale

Chronically low blood levels of oxygen may lead to pulmonary hypertension (high blood pressure in the lungs), and possibly to cor pulmonale. Cor pulmonale is also called right-sided heart failure, and is characterized by enlargement of the right ventricle. Treatment targets the underlying illness and may include supplemental oxygen, a low-salt diet or calcium channel blockers.

Illustration

Respiratory system - Illustration Thumbnail

Respiratory system

Air is breathed in through the nasal passageways, travels through the trachea and bronchi to the lungs.

Illustration

 
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