Blood thinners - aspirin; Antiplatelet therapy - aspirin
Current guidelines recommend that people with coronary artery disease (CAD) receive antiplatelet therapy with either aspirin or clopidogrel.
Aspirin therapy is very helpful for people with CAD or a history of stroke. If you have been diagnosed with CAD, your health care provider may recommend that you take a daily dose (from 75 to 162 mg) of aspirin. A daily dose of 81 mg is recommended for people who have had angioplasty (also called PCI). It is most often prescribed along with another antiplatelet medicine. Aspirin can reduce the risk for heart attack and ischemic stroke. However, using aspirin over the long-term can raise your risk for stomach bleeding.
Daily aspirin should not be used for prevention in healthy people who are at low risk for heart disease. You provider will consider your overall medical condition and risk factors for heart attack before recommending aspirin therapy.
Taking aspirin helps prevent blood clots from forming in your arteries and may help lower your risk for a stroke or heart attack.
Your provider may recommend to take daily aspirin if:
Aspirin helps get more blood flowing to your legs. It can treat a heart attack and prevent blood clots when you have an abnormal heartbeat. You probably will take aspirin after you have treatment for clogged arteries.
You will most likely take aspirin as a pill. A daily low-dose aspirin (75 to 81 mg) is most often the first choice for preventing heart disease or stroke.
Talk to your provider before taking aspirin every day. Your provider may change your dose from time to time.
Aspirin can have side effects such as:
Before you start taking aspirin, tell your provider if you have bleeding problems or stomach ulcers. Also say if you are pregnant or breastfeeding.
Take your aspirin with food and water. This can reduce side effects. You may need to stop taking this medicine before surgery or dental work. Always talk to your provider before you stop taking this medicine. If you have had a heart attack or a stent placed, be sure to ask your heart doctor if it is OK to stop taking aspirin.
You may need medicine for other health problems. Ask your provider if this is safe.
If you miss a dose of your aspirin, take it as soon as possible. If it is time for your next dose, take your usual amount. Do not take extra pills.
Store your medicines in a cool, dry place. Keep them away from children.
Contact your provider if you have side effects.
Side effects can be any signs of unusual bleeding:
Other side effects can be dizziness or difficulty swallowing.
Contact your provider if you have wheezing, breathing difficulty, or tightness or pain in your chest.
Side effects include swelling in your face or hands. Call your provider if you have itching, hives, or tingling in your face or hands, very bad stomach pain, or a skin rash.
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US Preventative Services Task Force; Davidson KW, Barry MJ, Mangione CM, et al. Aspirin use to prevent cardiovascular disease US Preventive Services Task Force Recommendation Statement. JAMA. 2022;327(16):1577-1584. PMID: 35471505 pubmed.ncbi.nlm.nih.gov/35471505/.
BACK TO TOPReview Date: 8/16/2022
Reviewed By: Michael A. Chen, MD, PhD, Associate Professor of Medicine, Division of Cardiology, Harborview Medical Center, University of Washington Medical School, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
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06/01/2025
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